A Multicenter Open-Label Randomized Controlled Trial of Pancreatic Enzyme Replacement Therapy in Unresectable Pancreatic Cancer
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DOI: 10.1097/mpa.0000000000001079
Abstract: Objective Exocrine pancreatic insufficiency may impair the nutritional status in pancreatic cancer (PC), but the role of pancreatic enzyme replacement therapy (PERT) is not fully evaluated. Therefore, we conducted this multicenter open-label randomized controlled trial… read more here.
Keywords: randomized controlled; enzyme replacement; pancreatic cancer; controlled trial ... See more keywords
Is Elevated Pancreatic Enzyme Level in Coronavirus Disease 2019 Patients a Silent Bystander?
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DOI: 10.1097/mpa.0000000000002015
Abstract: and 30.7% (n = 70) received both surgery and CT. Despite the very small sample size, CT did not significantly improve postoperative survival (P = 0.054). A total of 26 patients received postoperative radiation and… read more here.
Keywords: chemoradiotherapy; disease; pancreatic enzyme; enzyme level ... See more keywords
The Impact of Pancreatic Enzyme Replacement Therapy on Patients With Advanced Pancreatic Adenocarcinoma
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DOI: 10.1097/mpa.0000000000002049
Abstract: Abstract Advanced pancreatic cancer has a poor prognosis globally. Patients often develop pancreatic exocrine insufficiency leading to malabsorption. This systematic literature review explores the impact of pancreatic enzyme replacement therapy (PERT) on patients with advanced… read more here.
Keywords: replacement; replacement therapy; pancreatic enzyme; enzyme replacement ... See more keywords
Community Perspective on Pancreatic Enzyme Replacement Therapy in Cystic Fibrosis
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DOI: 10.1097/mpg.0000000000003606
Abstract: People with cystic fibrosis (CF) and exocrine pancreatic insufficiency must take pancreatic enzyme replacement therapy (PERT) to prevent malnutrition and gastrointestinal (GI) symptoms. Finding better ways to manage GI complaints is a high priority for… read more here.
Keywords: pancreatic enzyme; enzyme replacement; replacement therapy; cystic fibrosis ... See more keywords
Pancreatic enzyme activity in the bile of healthy cats and its association with biliary morphology
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DOI: 10.1111/jvim.16196
Abstract: Abstract Background In human medicine, congenital maljunction of the common bile duct (CBD) and main pancreatic duct (MPD), or pancreatobiliary maljunction (PBM), is a known cause of cholecystitis. Objective Pancreatic enzyme activity in the bile… read more here.
Keywords: activity bile; enzyme activity; healthy cats; pancreatic enzyme ... See more keywords
Case report: Proton pump inhibitor drug-related problem in pancreatic cancer patient unmasks pancreatic enzyme insufficiency
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DOI: 10.1177/10781552211038031
Abstract: Introduction Palliative care aims to improve the quality of life of patients with a life-limiting or life-threatening illness and is multifaceted involving comprehensive interdisciplinary assessments and interventions. Interdisciplinary palliative care in the setting of untreatable… read more here.
Keywords: pancreatic enzyme; pump inhibitor; proton pump;
Impact of pancreatic enzyme replacement therapy (PERT) on clinical outcomes in nonresected pancreatic cancer (PC): Initial results.
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DOI: 10.1200/jco.2021.39.3_suppl.400
Abstract: 400Background: Current NCCN guidelines recommend PERT use in PC patients (pts) with symptoms of EPI. However, little evidence exists regarding clinical outcomes following PERT use in PC pts, especi... read more here.
Keywords: pancreatic enzyme; enzyme replacement; therapy pert; impact pancreatic ... See more keywords
State of anxiety may be associated with exocrine pancreatic insufficiency in functional dyspepsia patients with pancreatic enzyme abnormalities
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DOI: 10.3164/jcbn.21-67
Abstract: We have reported that refractory functional dyspepsia patients with pancreatic enzyme abnormalities (FD-P). We tried to analyze the prevalence of exocrine pancreatic insufficiency (EPI) in FD-P patients to clarify whether the pathophysiology of FD patients… read more here.
Keywords: functional dyspepsia; pancreatic enzyme; enzyme abnormalities; dyspepsia patients ... See more keywords
Pancreatic Enzyme Replacement Therapy in Patients Undergoing First-Line Gemcitabine Plus nab-paclitaxel for Advanced Pancreatic Adenocarcinoma
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DOI: 10.3389/fonc.2021.688889
Abstract: Background The clinical consequences of pancreatic exocrine insufficiency and its treatment in advanced pancreatic ductal adenocarcinoma (PDAC) are poorly investigated. This retrospective study aims at investigating the pancreatic enzyme replacement therapy (PERT) use and its… read more here.
Keywords: replacement therapy; enzyme replacement; first line; advanced pancreatic ... See more keywords
Intestinal Absorption of Lipids Using a Pancreatic Enzyme-Free Nutritional Supplement in Patients with Cystic Fibrosis: A Randomized, Double-Blind, Crossover Pilot Trial
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DOI: 10.3390/nu14030680
Abstract: Nutritional supplements for patients with exocrine pancreatic insufficiency (EPI) typically utilize pancreatic enzyme replacement therapy (PERT) which is associated with gastrointestinal side effects. We evaluated serum triglyceride levels in patients with cystic fibrosis following consumption… read more here.
Keywords: cystic fibrosis; serum triglyceride; patients cystic; pancreatic enzyme ... See more keywords
Correlates of Pancreatic Enzyme Replacement Therapy Intake in Adults with Cystic Fibrosis: Results of a Cross-Sectional Study
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DOI: 10.3390/nu14071330
Abstract: Most people with cystic fibrosis (pwCF) develop pancreatic insufficiency and are treated with pancreatic enzyme replacement therapy (PERT). We aimed to describe the use of PERT and assess the correlates of PERT dose in adult… read more here.
Keywords: pancreatic enzyme; enzyme replacement; cystic fibrosis; lipase ... See more keywords