Editorial for “Evaluation of Pancreatic Fibrosis Grading by Multiparametric Functional Magnetic Resonance Imaging”
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.27697
Abstract: Editorial for “Evaluation of Pancreatic Fibrosis Grading by Multiparametric Functional Magnetic Resonance Imaging” Pancreatic fibrosis (PF) is detected in different diseases including chronic pancreatitis and pancreatic ductal adenocarcinoma and represents a reparative tissue response to… read more here.
Keywords: resonance imaging; fibrosis; magnetic resonance; evaluation ... See more keywords
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2021.110001
Abstract: BACKGROUND AND AIM Pancreatic fibrosis increases pancreatic cancer risk in chronic pancreatitis (CP). Pancreatic stellate cells (PSCs) play a critical role in the pathological processes of pancreatic fibrosis by transforming growth factor β (TGFβ) signal… read more here.
Keywords: hsp90 inhibitor; inhibitor 17aag; inhibitor; pancreatic fibrosis ... See more keywords
Pancreatic MRI associated with pancreatic fibrosis and postoperative fistula: comparison between pancreatic cancer and non-pancreatic cancer tissue.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical radiology"
DOI: 10.1016/j.crad.2019.02.013
Abstract: AIM To evaluate the potential value of magnetic resonance imaging (MRI) for predicting postoperative pancreatic fistula (POPF) in patients with pancreatic cancer (PC) and non-pancreatic cancer (non-PC). MATERIAL AND METHODS This retrospective study was approved… read more here.
Keywords: pancreatic cancer; cancer non; mri; cancer ... See more keywords
Amygdalin improves microcirculatory disturbance and attenuates pancreatic fibrosis by regulating the expression of endothelin‐1 and calcitonin gene‐related peptide in rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Chinese Medical Association"
DOI: 10.1016/j.jcma.2017.09.005
Abstract: Background: The pathogenesis of chronic pancreatitis (CP) is a complex process of interaction between tissue injury and repair, which involves microcirculatory disturbance. Amygdalin, an effective component extracted from Semen Persicae (a kind of Chinese herbal… read more here.
Keywords: fibrosis; endothelin calcitonin; expression; microcirculatory disturbance ... See more keywords
FTY720 inhibits the activation of pancreatic stellate cells by promoting apoptosis and suppressing autophagy via the AMPK/mTOR pathway
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.12.019
Abstract: Aims: Pancreatic stellate cells (PSCs) play a critical role in the development of pancreatic fibrosis. Any agents that can affect PSC activation could become potential candidates for treating pancreatic fibrosis. FTY720 can attenuate chronic pancreatic… read more here.
Keywords: mtor pathway; apoptosis; ampk mtor; activation ... See more keywords
Nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via α7nAChR-mediated JAK2/STAT3 signaling pathway in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.06.012
Abstract: AIM Smoking has been considered as a risk factor of chronic pancreatitis (CP), but the potential mechanism is still unknown. The major pathological feature of CP is pancreatic fibrosis, whose major functional cells are pancreatic… read more here.
Keywords: jak2 stat3; fibrosis; 7nachr mediated; mediated jak2 ... See more keywords
Association between pancreatic fibrosis and development of pancreoprivic diabetes after pancreaticoduodenectomy
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DOI: 10.1038/s41598-021-02858-z
Abstract: This study investigated the correlation between pancreatic fibrosis (PF) and development of pancreoprivic diabetes after pancreaticoduodenectomy (PD). Ninety-five patients who underwent PD at Gangnam Severance Hospital between 2014 and 2017 were enrolled. PF grade was… read more here.
Keywords: pancreoprivic diabetes; pancreoprivic; pancreatic fibrosis; fibrosis development ... See more keywords
Increased heat shock protein 70 expression attenuates pancreatic fibrosis induced by dibutyltin dichloride
Sign Up to like & getrecommendations! Published in 2018 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2018.1516799
Abstract: Abstract Objectives: Heat shock protein (HSP) 70 performs a chaperoning function and protects cells against injury. Although the effect of HSPs against acute inflammatory change has been proven, the relationship between HSP70 and chronic pancreatitis… read more here.
Keywords: increased hsp70; thermal stress; hsp70 expression; expression ... See more keywords
Preoperative Evaluation of Pancreatic Fibrosis and Lipomatosis: Correlation of Magnetic Resonance Findings With Histology Using Magnetization Transfer Imaging and Multigradient Echo Magnetic Resonance Imaging
Sign Up to like & getrecommendations! Published in 2018 at "Investigative Radiology"
DOI: 10.1097/rli.0000000000000496
Abstract: Objectives The purpose of this study was to evaluate the diagnostic performance of magnetization transfer (MT) imaging and multigradient echo magnetic resonance imaging (MRI) to quantify pancreatic fibrosis and lipomatosis in patients before pancreatoduodenectomy for… read more here.
Keywords: fibrosis; magnetic resonance; lipomatosis; pancreatic fibrosis ... See more keywords
Hic‐5 deficiency protects cerulein‐induced chronic pancreatitis via down‐regulation of the NF‐κB (p65)/IL‐6 signalling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14833
Abstract: Chronic pancreatitis (CP), characterized by pancreatic fibrosis, is a recurrent, progressive and irreversible disease. Activation of the pancreatic stellate cells (PSCs) is considered a core event in pancreatic fibrosis. In this study, we investigated the… read more here.
Keywords: signalling pathway; p65 signalling; chronic pancreatitis; cerulein induced ... See more keywords
Characterization of Macrophages and Myofibroblasts Appearing in Dibutyltin Dichloride–Induced Rat Pancreatic Fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "Toxicologic Pathology"
DOI: 10.1177/0192623319893310
Abstract: Macrophages and myofibroblasts are important in fibrogenesis. The cellular characteristics in pancreatic fibrosis remain to be investigated. Pancreatic fibrosis was induced in F344 rats by a single intravenous injection of dibutyltin dichloride. Histopathologically, the induced… read more here.
Keywords: fibrosis; dibutyltin dichloride; macrophages myofibroblasts; mesenchymal cells ... See more keywords