Dietary l-lysine supplementation altered the content of pancreatic polypeptide, enzymes involved in glutamine metabolism, and β-actin in rats
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2648-x
Abstract: This study investigated the effects of Lys supplementation on serum pancreatic polypeptide (PP), glutamine (Gln) levels and the expression of PP, Gln synthetase (GlnS), glutaminase (Gls) and β-actin in different tissues such as pancreas, skeletal… read more here.
Keywords: supplementation; actin; muscle; lys ... See more keywords
Reduced Pancreatic polypeptide Response is associated with early alteration of glycemic control in chronic pancreatitis.
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2019.107993
Abstract: AIM To study the incidence of glucose intolerance in CP patients without diabetes by performing oral glucose tolerance test (OGTT). METHODS We screened consecutive Indian CP patients without diabetes over 6 months by performing OGTT… read more here.
Keywords: response; pancreatic polypeptide; polypeptide response; reduced pancreatic ... See more keywords
Pancreatic Polypeptide Cell Proliferation in the Pancreas and Duodenum Coexisting in a Patient With Pancreatic Adenocarcinoma Treated With a GLP-1 Analog
Sign Up to like & getrecommendations! Published in 2017 at "Pancreas"
DOI: 10.1097/mpa.0000000000000844
Abstract: Abstract A partial pancreaticogastrodudenectomy was performed on a 66-year old man with type 2 diabetes mellitus because of an invasive, moderately differentiated adenocarcinoma in the head of the pancreas. In the adjacent grossly normal tissue… read more here.
Keywords: pancreatic adenocarcinoma; glp analog; proliferation; pancreatic polypeptide ... See more keywords
Degradation Paradigm of the Gut Hormone, Pancreatic Polypeptide, by Hepatic and Renal Peptidases
Sign Up to like & getrecommendations! Published in 2017 at "Endocrinology"
DOI: 10.1210/en.2016-1827
Abstract: Pancreatic polypeptide (PP) is a gut hormone that acts on Y4 receptors to reduce appetite. Obese humans display a reduced postprandial increase in PP and remain fully sensitive to the anorectic effects of exogenous PP.… read more here.
Keywords: degradation; pancreatic polypeptide; gut hormone;
Establishment of an enzyme-linked immunosorbent assay for mouse pancreatic polypeptide clarifies the regulatory mechanism of its secretion from pancreatic γ cells
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0269958
Abstract: Pancreatic polypeptide (PP), secreted from γ cells of the islets of Langerhans, is a 36 amino-acid peptide encoded by the Ppy gene. Although previous studies have reported that PP causes a decrease in appetite, the… read more here.
Keywords: pancreatic polypeptide; mouse; secretion; mechanism secretion ... See more keywords
Supraphysiological effects of pancreatic polypeptide on gastric motor function and nutrient tolerance in humans
Sign Up to like & getrecommendations! Published in 2021 at "Physiological Reports"
DOI: 10.14814/phy2.15002
Abstract: Pancreatic polypeptide (PP) is known to affect food intake. In this exploratory study, we set out to investigate its supraphysiological effect on food tolerance, gastric accommodation, and emptying. In 12 healthy volunteers, 0, 3, or… read more here.
Keywords: pp10 respectively; pp0; pp0 pp3; tolerance ... See more keywords
Pancreatic Polypeptide in Parkinson's Disease: A Potential Marker of Parasympathetic Denervation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Parkinson's disease"
DOI: 10.3233/jpd-171189
Abstract: BACKGROUND AND OBJECTIVES Parkinson's disease (PD) patients experience several non-motor symptoms from the gastrointestinal tract that may partly be caused by parasympathetic deficiency. The pancreas is densely innervated by the vagus nerve, which mediates early… read more here.
Keywords: sham feeding; pancreatic polypeptide; denervation; marker ... See more keywords
Pancreatic Polypeptide but Not Other Members of the Neuropeptide Y Family Shows a Moderate Association With Perceived Anxiety in Obese Men
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Human Neuroscience"
DOI: 10.3389/fnhum.2020.578578
Abstract: Neuropeptide Y (NPY), peptide tyrosine tyrosine (PYY), and pancreatic polypeptide (PP) are important mediators in the bidirectional communication along the gut-brain-axis. Best known for their role in the regulation of appetite and food intake they… read more here.
Keywords: family shows; anxiety; polypeptide members; neuropeptide family ... See more keywords