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   Articles with "paneth cells" as a keyword



Paneth cells and their multiple functions.

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recommendations! Published in 2022 at "Cell biology international"

DOI: 10.1002/cbin.11764

Abstract: The small intestine mucosa is lined by specialized cells that form the crypt-villus axis, which expands its surface. Among the six intestinal epithelial cell types, the Paneth cell is located at the base of the… read more here.

Keywords: multiple functions; cell; cells multiple; paneth cells ... See more keywords

Synergistic effect of aluminum and ionizing radiation upon ultrastructure, oxidative stress and apoptotic alterations in Paneth cells of rat intestine

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recommendations! Published in 2017 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-017-8392-z

Abstract: Environmental and occupational exposure to aluminum along with ionizing radiation results in serious health problems. This study was planned to investigate the impact of oxidative stress provoked by exposure to ionizing radiation with aluminum administration… read more here.

Keywords: aluminum; ionizing radiation; paneth cells; oxidative stress ... See more keywords

Erratum to: Synergistic effect of aluminum and ionizing radiation upon ultrastructure, oxidative stress and apoptotic alterations in Paneth cells of rat intestine

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recommendations! Published in 2017 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-017-9286-9

Abstract: Environmental and occupational exposure to aluminum along with ionizing radiation results in serious health problems. This study was planned to investigate the impact of oxidative stress provoked by exposure to ionizing radiation with aluminum administration… read more here.

Keywords: aluminum; ionizing radiation; paneth cells; oxidative stress ... See more keywords

Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1,2-fucose in the small intestine.

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recommendations! Published in 2020 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2020.108653

Abstract: The modification of galactose with α1,2-fucose is involved in symbiosis with intestinal bacteria and elimination of pathogenic bacteria. It is postulated that α1,2-fucosylated mucin secreted from goblet cells is involved in defending an organism against… read more here.

Keywords: related sequence; paneth cells; glycoproteomic analysis; small intestine ... See more keywords

Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling.

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recommendations! Published in 2018 at "Cell reports"

DOI: 10.1016/j.celrep.2018.07.085

Abstract: IBD syndromes such as Crohn's disease and ulcerative colitis result from the inflammation of specific intestinal segments. Although many studies have reported on the regenerative response of intestinal progenitor and stem cells to tissue injury,… read more here.

Keywords: response; paneth cells; inflammation; tissue ... See more keywords
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Paneth cells mediated the response of intestinal stem cells at the early stage of intestinal inflammation in the chicken.

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recommendations! Published in 2021 at "Poultry science"

DOI: 10.1016/j.psj.2020.11.055

Abstract: The rapid renewal and repair of the intestinal mucosa are based on intestinal stem cells (ISC), which are located at the crypt bottom. Paneth cells are an essential component in the crypt, which served as… read more here.

Keywords: hpi; intestinal inflammation; paneth cells; crypt ... See more keywords

Mouse Paneth Cell-Enriched Proteome Enabled by Laser Capture Microdissection.

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recommendations! Published in 2022 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.2c00311

Abstract: Paneth cells are antimicrobial peptide-secreting cells located at the base of the crypts of the small intestine. The proteome of Paneth cells is not well defined because of their coexistence with stem cells, making it… read more here.

Keywords: capture microdissection; cell; laser capture; paneth cells ... See more keywords
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Paneth cell alertness to pathogens maintained by vitamin D receptors.

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recommendations! Published in 2020 at "Gastroenterology"

DOI: 10.1053/j.gastro.2020.11.015

Abstract: BACKGROUND Vitamin D exerts a regulatory role over mucosal immunity via the vitamin D receptor (VDR). While Paneth cells and their products are known to regulate the commensal and pathogenic microbiota, the role that VDRs… read more here.

Keywords: vdr mice; cell alertness; vdr; paneth cell ... See more keywords

Intestinal TLR4 deletion exacerbates acute pancreatitis through gut microbiota dysbiosis and Paneth cells deficiency

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recommendations! Published in 2022 at "Gut Microbes"

DOI: 10.1080/19490976.2022.2112882

Abstract: ABSTRACT Toll-like receptor 4 (TLR4) has been identified as a potentially promising therapeutic target in acute pancreatitis (AP). However, the role of intestinal TLR4 in AP and AP-associated gut injury remains unclear. This study aimed… read more here.

Keywords: paneth cells; tlr4; intestinal tlr4; gut microbiota ... See more keywords

P147 IBD relevant pathways are upregulated in Paneth cells in a murine model of dietary induced intestinal inflammation

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recommendations! Published in 2024 at "Journal of Crohn's and Colitis"

DOI: 10.1093/ecco-jcc/jjad212.0277

Abstract: Dietary constituents are believed to play a role in the development of Crohn’s disease (CD) (1). Recently we were able to demonstrate, that polyunsaturated fatty acids (PUFA), induce a CD like enteritis phenotype in genetically… read more here.

Keywords: paneth cells; intestinal inflammation; relevant pathways; ibd relevant ... See more keywords

DEVELOPMENT OF A PERSONALIZED HUMAN PANETH CELL MODEL USING INTESTINAL ORGANOIDS

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recommendations! Published in 2024 at "Inflammatory Bowel Diseases"

DOI: 10.1093/ibd/izae020.186

Abstract: Paneth cells are a specialized intestinal epithelial cell subtype whose major function is to produce antimicrobial peptides (AMPs). Alterations in Paneth cell function are associated with Crohn’s disease (CD) but the confounding influences of environmental… read more here.

Keywords: paneth cells; significantly increased; paneth; cell ... See more keywords