Articles with "pangenome analysis" as a keyword



Pangenome analysis reveals structural variation associated with seed size and weight traits in peanut

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Published in 2025 at "Nature Genetics"

DOI: 10.1038/s41588-025-02170-w

Abstract: Peanut (Arachis hypogaea L.) is an important oilseed and food legume crop, with seed size and weight being critical traits for domestication and breeding. However, genomic rearrangements like structural variations (SVs) underlying seed size and… read more here.

Keywords: seed; size; size weight; seed size ... See more keywords

A pangenome analysis of ESKAPE bacteriophages: the underrepresentation may impact machine learning models

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Published in 2024 at "Frontiers in Molecular Biosciences"

DOI: 10.1101/2024.02.19.581114

Abstract: Bacteriophages are the most prevalent biological entities in the biosphere. However, limitations in both medical relevance and sequencing technologies have led to a systematic underestimation of the genetic diversity within phages. This underrepresentation not only… read more here.

Keywords: eskape; phage; analysis eskape; underrepresentation ... See more keywords

Combing Immunoinformatics with Pangenome Analysis To Design a Multiepitope Subunit Vaccine against Klebsiella pneumoniae K1, K2, K47, and K64

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Published in 2022 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.01148-22

Abstract: Klebsiella pneumoniae is an opportunistic Gram-negative bacterium that has become a leading causative agent of nosocomial infections. Among the numerous capsular serotypes, K1, K2, K47, and K64 are commonly associated with higher virulence (hypervirulent K.… read more here.

Keywords: k47 k64; pneumoniae; pangenome analysis; klebsiella pneumoniae ... See more keywords

Pangenome Analysis of a Salmonella Enteritidis Population Links a Major Outbreak to a Gifsy-1-Like Prophage Containing Anti-Inflammatory Gene gogB

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Published in 2023 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.02791-22

Abstract: We examined 5 years of genomic and epidemiological data for the significant global foodborne pathogen, Salmonella enterica. Although Salmonella enterica subspecies enterica serovar Enteritidis (S. Enteritidis) is the leading cause of salmonellosis in the USA… read more here.

Keywords: prophage; pangenome analysis; salmonella; enteritidis ... See more keywords

Pangenome analysis reveals transposon-driven genome evolution in cotton

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Published in 2024 at "BMC Biology"

DOI: 10.1186/s12915-024-01893-2

Abstract: Transposable elements (TEs) have a profound influence on the trajectory of plant evolution, driving genome expansion and catalyzing phenotypic diversification. The pangenome, a comprehensive genetic pool encompassing all variations within a species, serves as an… read more here.

Keywords: evolution; genome evolution; analysis reveals; cotton ... See more keywords

APAV: An advanced pangenome analysis and visualization toolkit

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Published in 2025 at "PLOS Computational Biology"

DOI: 10.1371/journal.pcbi.1013288

Abstract: Traditional pangenome analysis focuses on gene presence/absence variations (gene PAVs). However, the current methods for gene PAV analysis are insensitive to detect small but valuable mutations within gene regions, and they overlook variations in intergenic… read more here.

Keywords: analysis; pav analysis; analysis visualization; gene ... See more keywords

Integrated Pangenome Analysis and Pharmacophore Modeling Revealed Potential Novel Inhibitors against Enterobacter xiangfangensis

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Published in 2022 at "International Journal of Environmental Research and Public Health"

DOI: 10.3390/ijerph192214812

Abstract: Enterobacter xiangfangensis is a novel, multidrug-resistant pathogen belonging to the Enterobacter genus and has the ability to acquire resistance to multiple antibiotic classes. However, there is currently no registered E. xiangfangensis drug on the market… read more here.

Keywords: pangenome analysis; xiangfangensis; analysis; integrated pangenome ... See more keywords