Pangenome-based genome inference allows efficient and accurate genotyping across a wide spectrum of variant classes.
Sign Up to like & getrecommendations! Published in 2022 at "Nature genetics"
DOI: 10.1038/s41588-022-01043-w
Abstract: Typical genotyping workflows map reads to a reference genome before identifying genetic variants. Generating such alignments introduces reference biases and comes with substantial computational burden. Furthermore, short-read lengths limit the ability to characterize repetitive genomic… read more here.
Keywords: genome inference; pangenome based; genotyping; wide spectrum ... See more keywords
Pangenome-based trajectories of intracellular gene transfers in Poaceae unveil high cumulation in Triticeae.
Sign Up to like & getrecommendations! Published in 2023 at "Plant physiology"
DOI: 10.1093/plphys/kiad319
Abstract: Intracellular gene transfers (IGTs) between the nucleus and organelles, including plastids and mitochondria, constantly reshape the nuclear genome during evolution. Despite the substantial contribution of IGTs to genome variation, the dynamic trajectories of IGTs at… read more here.
Keywords: trajectories intracellular; gene transfers; intracellular gene; pangenome based ... See more keywords