Novel recurrence risk stratification of resected pancreatic neuroendocrine tumor.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.10.036
Abstract: Radical surgical resection represents the only hope of cure for pancreatic neuroendocrine tumor (PanNET). Adjuvant therapy is rarely used because there is no evidence to distinguish patients with high recurrence risk. Here we investigated the… read more here.
Keywords: risk; recurrence risk; recurrence; pannet ... See more keywords
MEN1 degradation induced by neddylation and the CUL4B-DCAF7 axis promotes pancreatic neuroendocrine tumor progression.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-3599
Abstract: Pancreatic neuroendocrine tumors (PanNETs) are a group of rare sporadic malignant tumors in the pancreas. MEN1 is the most frequently mutated gene in PanNETs. The MEN1-encoded protein is a typical tumor suppressor that forms a… read more here.
Keywords: neddylation; expression; men1; pannet ... See more keywords
Poor outcome after systemic therapy in secondary high-grade pancreatic neuroendocrine tumors
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DOI: 10.1530/ec-21-0604
Abstract: Longitudinal changes in pancreatic neuroendocrine tumor (panNET) cell proliferation correlate with fast disease progression and poor prognosis. The optimal treatment strategy for secondary panNET grade (G)3 that has progressed from a previous low- or intermediate-grade… read more here.
Keywords: high grade; grade; pannet; months iqr ... See more keywords