Electrophysiological characteristics of Panx1 channel and its purinergic regulation by P2X7 receptor
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5723669
Abstract: Background: Extracellular ATP is a key mediator of evolutionary conserved purinergic signaling, which regulates many biological effects (tissue homeostasis, immunity, inflammation, healing etc.) and is involved in the pathogenesis of diseases of the immune, nervous,… read more here.
Keywords: p2x7 receptor; physiology; panx1 channel;
Mechanisms of Pannexin 1 (PANX1) Channel Mechanosensitivity and Its Pathological Roles
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DOI: 10.3390/ijms23031523
Abstract: Pannexins (PANX) were cloned based on their sequence homology to innexins (Inx), invertebrate gap junction proteins. Although there is no sequence homology between PANX and connexins (Cx), these proteins exhibit similar configurations. The PANX family… read more here.
Keywords: channel mechanosensitivity; pathological roles; panx1; mechanisms pannexin ... See more keywords