Pannexin1 channels—a potential therapeutic target in inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1020826
Abstract: An exaggerated inflammatory response is the hallmark of a plethora of disorders. ATP is a central signaling molecule that orchestrates the initiation and resolution of the inflammatory response by enhancing activation of the inflammasome, leukocyte… read more here.
Keywords: inflammation; inflammatory response; panx1; panx1 channels ... See more keywords
Inhibition of PANX1 Channels Reduces the Malignant Properties of Human High-Risk Neuroblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cancer"
DOI: 10.7150/jca.79552
Abstract: Pannexin 1 (PANX1) is expressed in many tissue types including tissues of neural origin. Neuroblastoma (NB) is a neural crest-derived malignancy mainly occurring in children. The majority of NB patients present with high-risk disease for… read more here.
Keywords: inhibition; high risk; malignant properties; panx1 channels ... See more keywords