Pannexin 1 regulates adipose stromal cell differentiation and fat accumulation
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DOI: 10.1038/s41598-018-34234-9
Abstract: Pannexin 1 (Panx1) is a channel-forming glycoprotein important in paracrine signaling and cellular development. In this study, we discovered that mice globally lacking Panx1 (KO) have significantly greater total fat mass and reduced lean mass… read more here.
Keywords: panx1; fat accumulation; differentiation; adipose stromal ... See more keywords
Ablation of both Cx40 and Panx1 results in similar cardiovascular phenotypes exhibited in Cx40 knockout mice
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DOI: 10.1042/bsr20182350
Abstract: Connexins (Cxs) and pannexins (Panxs) are highly regulated large-pore channel-forming proteins that participate in cellular communication via small molecular exchange with the extracellular microenvironment, or in the case of connexins, directly between cells. Given the… read more here.
Keywords: cx40 panx1; knockout mice; mice; panx1 mice ... See more keywords