Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritis.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biology international"
DOI: 10.1002/cbin.12010
Abstract: Pannexin 3 (Panx3) is involved in regulation of the proliferation and differentiation in chondrocytes and pathological process in osteoarthritis, but its role and potential mechanism in temporomandibular joint osteoarthritis (TMJOA) are still unclear, which are… read more here.
Keywords: inflammation; matrix degradation; cartilage; panx3 ... See more keywords
The Role of Pannexin 3 in Bone Biology
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Dental Research"
DOI: 10.1177/0022034516678203
Abstract: Cell–cell and cell–matrix communications play important roles in both cell proliferation and differentiation. Gap junction proteins mediate signaling communication by exchanging small molecules and dramatically stimulating intracellular signaling pathways to determine cell fate. Vertebrates have… read more here.
Keywords: gap junction; biology; differentiation; panx3 ... See more keywords
A Potential Compensatory Role of Panx3 in the VNO of a Panx1 Knock Out Mouse Model
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00135
Abstract: Pannexins (Panx) are integral membrane proteins, with Panx1 being the best-characterized member of the protein family. Panx1 is implicated in sensory processing, and knockout (KO) animal models have become the primary tool to investigate the… read more here.
Keywords: loss panx1; panx1; expression; role ... See more keywords