Pretreatment antigen-specific immunity and regulation - association with subsequent immune response to anti-tumor DNA vaccination
Sign Up to like & getrecommendations! Published in 2017 at "Journal for Immunotherapy of Cancer"
DOI: 10.1186/s40425-017-0260-3
Abstract: Background Immunotherapies have demonstrated clinical benefit for many types of cancers, however many patients do not respond, and treatment-related adverse effects can be severe. Hence many efforts are underway to identify treatment predictive biomarkers. We… read more here.
Keywords: immunity; antigen specific; pap specific; antigen ... See more keywords
A Mutated Prostatic Acid Phosphatase (PAP) Peptide-Based Vaccine Induces PAP-Specific CD8+ T Cells with Ex Vivo Cytotoxic Capacities in HHDII/DR1 Transgenic Mice
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14081970
Abstract: Simple Summary Treatments for castrate (hormone)-resistant prostate cancer (CRPC) remain limited and are not curative. Although the first (and only) FDA-approved vaccine for CRPC (PROVENGE®, Sipuleucel-T) has been shown to improve the overall survival of… read more here.
Keywords: specific cd8; cd8 cells; pap specific; pap ... See more keywords