Overexpression of the pro-protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13396
Abstract: Furin belongs to the pro-protein convertases (PCs) family and its aberrant expression has been documented in various types of cancers; however, its role in thyroid cancer remains unclear. We investigated the expression of furin in… read more here.
Keywords: thyroid carcinoma; furin; ptc; braf ... See more keywords
Spatial and Single‐Cell Transcriptomics Unraveled Spatial Evolution of Papillary Thyroid Cancer
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202404491
Abstract: Recurrence and metastasis are the major issues for papillary thyroid cancer (PTC). Current morphological and molecular classification systems are not satisfied for PTC diagnosis due to lacking variant‐specific morphological criteria and high signal‐to‐noise in mutation‐based… read more here.
Keywords: evolution; single cell; spatial single; thyroid cancer ... See more keywords
Identification and Validation of Prognostic Signature of Papillary Thyroid Carcinoma Based on Six Immune-Related lncRNAs.
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.70063
Abstract: This research seeks to identify and verify the prognostic signature of immune-related RNA of papillary thyroid carcinoma (PTC). The Cancer Genome Atlas (TCGA) database provided the PTC samples and clinical data. Using the limma program,… read more here.
Keywords: ptc; signature; thyroid carcinoma; immune related ... See more keywords
Surgeon volume and prognosis of patients with advanced papillary thyroid cancer and lateral nodal metastasis
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Surgery"
DOI: 10.1002/bjs.10655
Abstract: Surgery is the most important treatment modality for papillary thyroid cancer (PTC). However, the relationship between surgeon volume and long‐term oncological outcomes has not been explored. read more here.
Keywords: papillary thyroid; surgeon volume; thyroid cancer;
Extensive lymphatic spread of papillary thyroid microcarcinoma is associated with an increase in expression of genes involved in epithelial‐mesenchymal transition and cancer stem cell‐like properties
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2544
Abstract: Active surveillance is an alternative management for patents with low‐risk papillary thyroid microcarcinoma (PTMC); however, there is an absence of specific molecular markers that predict its progression. We compared gene expression patterns between PTMC with… read more here.
Keywords: papillary thyroid; expression; thyroid microcarcinoma; cancer ... See more keywords
MicroRNA profiling predicts positive nodal status in papillary thyroid carcinoma in the preoperative setting
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22585
Abstract: The molecular characterization of thyroid nodules in cytological samples has so far been focused on discriminating between benign and malignant forms in a purely diagnostic setting. The evidence on the impact of molecular biomarkers to… read more here.
Keywords: papillary thyroid; nodal status; microrna profiling; profiling predicts ... See more keywords
Fine needle aspiration cytology of the papillary thyroid carcinoma with a solid component: A cytological and clinical correlation
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.23679
Abstract: Solid variant of papillary thyroid carcinoma is a rare subtype of papillary thyroid carcinoma (PTC) containing a solid component (SC), and thus its cytological and clinicopathological features remain elusive. We examined fine needle aspiration (FNA)… read more here.
Keywords: papillary thyroid; thyroid carcinoma; cytology; solid component ... See more keywords
Hobnail variant of papillary thyroid carcinoma: A case with an unusual presentation
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.23723
Abstract: Variants of papillary thyroid carcinoma (PTC) account for up to 25% of the cases, some of which are proven to be associated with aggressive clinical behavior such as tall cell and columnar cell variants. Hobnail… read more here.
Keywords: carcinoma; hobnail variant; papillary thyroid; hobnail ... See more keywords
A case report of papillary thyroid carcinoma dedifferentiated to squamous cell carcinoma presenting as a lung metastasis: A potential diagnostic pitfall
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24422
Abstract: Papillary thyroid carcinoma (PTC) tall cell variant (TCV) with squamous dedifferentiation is a rare entity. We present a case of 90‐year‐old woman who initially had a 2.8 cm conventional PTC in right lobe of thyroid who,… read more here.
Keywords: carcinoma; papillary thyroid; cell carcinoma; squamous cell ... See more keywords
Atypical histiocytoid cells in fine‐needle aspiration cytology of metastatic papillary thyroid carcinoma: A potential diagnostic pitfall
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24932
Abstract: Fine needle aspiration (FNA) cytology of cervical lymph nodes is an effective diagnostic tool to detect metastatic papillary thyroid carcinoma (PTC) when typical cytomorphologic features of PTC are observed. However, the presence of atypical histiocytoid… read more here.
Keywords: thyroid carcinoma; fine needle; needle aspiration; cytology ... See more keywords
TERT promoter mutation in primary papillary thyroid carcinoma lesions predicts absent or lower 131i uptake in metastases
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2056
Abstract: Genetic mutations play important roles in not only development of papillary thyroid carcinoma (PTC) but also determination of its properties. The radioactive iodine refractory (RAIR) state is a harbinger of poor outcomes for PTC. We… read more here.
Keywords: papillary thyroid; group; rair; tert mutation ... See more keywords