A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive Tract
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DOI: 10.1128/mbio.00180-19
Abstract: Tractable and efficient models of papillomavirus-induced pathogenesis are limited due to the strict species-specific and tissue-specific tropism of these viruses. Here, we report a novel preclinical murine model of papillomavirus-induced cervicovaginal disease in wild-type, immunocompetent… read more here.
Keywords: infection; papillomavirus induced; mmupv1; model ... See more keywords
Human Papillomavirus–Induced Cancer: Late Relapse in a Patient Treated With Tumor Necrosis Factor-Alpha Inhibitor
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DOI: 10.1200/jgo.2016.005835
Abstract: In 1989, a 48-year-old white woman with wellcontrolled hypertension and type 2 diabetes was treated with abdominoperineal resection with definitive colostomy because of a 4-cm anal squamous cell cancerous tumor, with zero of four lymph… read more here.
Keywords: relapse patient; induced cancer; papillomavirus induced; human papillomavirus ... See more keywords
Efficacy of Topically Administered Dihydroartemisinin in Treating Papillomavirus-Induced Anogenital Dysplasia in Preclinical Mouse Models
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DOI: 10.3390/v14081632
Abstract: The artemisinin family of compounds is cytopathic in certain cancer cell lines that are positive for human papillomaviruses (HPV) and can potentially drive the regression of dysplastic lesions. We evaluated the efficacy of topical dihydroartemisinin… read more here.
Keywords: papillomavirus; papillomavirus induced; mice; mouse models ... See more keywords