Resolving the APN controversy in PEDV infection: Comparative kinetic characterization through single-virus tracking
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DOI: 10.1371/journal.ppat.1013317
Abstract: Aminopeptidase N (APN) plays multiple roles in various physiological processes, with its function as a viral receptor in several coronaviruses being one of the most prominent. However, the role of porcine APN (pAPN) in porcine… read more here.
Keywords: papn; internalization; virus; single virus ... See more keywords
CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production performance
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.57132
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) and transmissible gastroenteritis virus (TGEV) are two highly infectious and lethal viruses causing major economic losses to pig production. Here, we report generation of double-gene-knockout (DKO) pigs harboring… read more here.
Keywords: papn; dko pigs; cd163 papn; pdcov ... See more keywords