Tipping the PARylation scale: Dysregulation of PAR signaling in Huntington and neurodegenerative diseases
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DOI: 10.1177/18796397251372667
Abstract: Poly(ADP-ribosyl)ation (PARylation), a crucial post-translational modification, is catalyzed by ADP-ribosyltransferases (ARTs) and has significant implications in various cellular processes, including DNA damage response, cell signaling, and immune processes. Aberrant PAR signaling is implicated in numerous… read more here.
Keywords: dysregulation par; parylation; par signaling; neurodegenerative diseases ... See more keywords