Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain
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DOI: 10.1073/pnas.2112059119
Abstract: Significance Colonic epithelial cells protect against inflammation by forming a barrier against ingress of microbes, digestive enzymes, and metabolic waste from the lumen. Protease-activated receptor-2 (PAR2) mediates the proinflammatory and pronociceptive actions of proteases. We… read more here.
Keywords: inflammation; par2 mugfp; endocytosis; mice ... See more keywords