LAUSR

Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity

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0 Published in 2017 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e16-07-0541

Abstract: The polarity regulator Par3 directs the reorganization of the apical membrane in polarized cells through the action of phosphatidylinositol 3-kinase and the Rac1 exchange factor Tiam1. This mechanism may be exploited by pathogens to bypass… read more here.

Keywords: par3 integrates; apical membrane; phosphatidylinositol kinase;