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Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.3c01867
Abstract: Marchantia species were traditionally used to treat liver failure. Marchantia polymorpha chloroform extract showed a marked hepatoprotective activity in a dose-dependent manner in paracetamol-induced extensive liver damage in mice. At a dose of 500 mg/kg…
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Keywords:
hepatoprotective activity;
marchantia;
activity;
metabolic profiling ... See more keywords
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Published in 2022 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2022.2052891
Abstract: Paracetamol-induced hepatotoxicity (APAP) causes severe damage that may be irreversible. Understanding the evolution of liver injury caused by overdose of the drug is important to assist in the treatment. In the present study, we evaluated…
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Keywords:
induced hepatotoxicity;
temporal analysis;
analysis paracetamol;
paracetamol induced ... See more keywords
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Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.7.6
Abstract: Parthenium hysterophorus is conventionally used to treat urinary tract infections, joint pain, and hyperglycaemia. This study evaluates the reno-curative effects of methanolic extract of P. hysterophorus (MEPH) in paracetamol-induced nephrotoxic rabbits. Thirty male rabbits were…
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Keywords:
hysterophorus;
meph;
paracetamol induced;
parthenium hysterophorus ... See more keywords
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Published in 2023 at "Pharmaceutical nanotechnology"
DOI: 10.2174/2211738511666230601105536
Abstract: INTRODUCTION Curcumin is a naturally occurring compound that has antioxidant properties, acts as a hepatoprotective, and lowers lipid peroxidation. However, curcumin's low solubility and bioavailability are its primary drawbacks and prevent its use as a…
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Keywords:
curcumin;
pure curcumin;
group;
curcumin nanoparticles ... See more keywords
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Published in 2023 at "General physiology and biophysics"
DOI: 10.4149/gpb_2022055
Abstract: Toxic doses of paracetamol are also known to be close to therapeutic doses. This study aimed to biochemically investigate the protective effect of ATP against paracetamol-induced oxidative liver injury in rats and to examine the…
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Keywords:
paracetamol;
patp;
protective effect;
induced liver ... See more keywords