Fomepizole should not be used more liberally in paracetamol overdose
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15596
Abstract: Fomepizole is a promising new treatment for preventing liver injury following paracetamol (acetaminophen) overdose. However, we need robust clinical trials to be performed to demonstrate its effect on clinical outcomes that are important to our… read more here.
Keywords: toxicology; pharmacology; liberally paracetamol; used liberally ... See more keywords
Paracetamol overdose causing acute kidney injury without hepatotoxicity: a case report
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DOI: 10.1186/s12245-024-00662-w
Abstract: Paracetamol is a widely used analgesic and antipyretic. Paracetamol-induced hepatotoxicity is well known, but nephrotoxicity without hepatotoxicity is rarely seen. We present a case of acute kidney injury without hepatotoxicity in paracetamol overdose. A 15-year-old… read more here.
Keywords: without hepatotoxicity; paracetamol overdose; kidney injury; acute kidney ... See more keywords
Rapid and non-invasive analysis of paracetamol overdose using paper arrow-mass spectrometry: a prospective observational study
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DOI: 10.1186/s12916-024-03776-3
Abstract: Paracetamol is the most consumed medicine globally. Its accessibility contributes to common overdose. Paracetamol overdose is responsible for > 50% of acute liver failure cases, making it the second most common reason for a liver transplant. Rapid… read more here.
Keywords: paper arrow; analysis; paracetamol overdose; medicine ... See more keywords
Paracetamol overdose: limiting the potential for harm
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DOI: 10.5694/mja2.50306
Abstract: Paracetamol is the pharmaceutical agent most frequently taken for deliberate selfpoisoning by adults and adolescents in Australia, the United Kingdom, and other developed countries.1 It is primarily taken in overdose by younger women, in most… read more here.
Keywords: paracetamol overdose; limiting potential; overdose limiting; potential harm ... See more keywords