Copper overload in Paracoccidioides lutzii results in the accumulation of ergosterol and melanin.
Sign Up to like & getrecommendations! Published in 2020 at "Microbiological research"
DOI: 10.1016/j.micres.2020.126524
Abstract: Paracoccidioidomycosis is a highly prevalent systemic mycosis in Latin America, caused by fungi of the genus Paracoccidioides. Copper is essential for eukaryotes and bacteria. This micronutrient is used in many vital biochemical processes, although metal… read more here.
Keywords: copper overload; accumulation; melanin; paracoccidioides lutzii ... See more keywords
Decyl Gallate as a Possible Inhibitor of N-Glycosylation Process in Paracoccidioides lutzii
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DOI: 10.1128/aac.01909-18
Abstract: The available antifungal therapeutic arsenal is limited. The search for alternative drugs with fewer side effects and new targets remains a major challenge. Decyl gallate (G14) is a derivative of gallic acid with a range… read more here.
Keywords: decyl gallate; process; glycosylation; activity ... See more keywords
Identification of Potentially Therapeutic Immunogenic Peptides From Paracoccidioides lutzii Species
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DOI: 10.3389/fimmu.2021.670992
Abstract: Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin America caused by the thermodimorphic fungi of the genus Paracoccidioides spp. Paracoccidioides lutzii (PL) is one of the 5 species that constitute the Paracoccidioides genus. PL expresses… read more here.
Keywords: cell; potentially therapeutic; paracoccidioides lutzii; dendritic cells ... See more keywords
Beyond Melanin: Proteomics Reveals Virulence-Related Proteins in Paracoccidioides brasiliensis and Paracoccidioides lutzii Yeast Cells Grown in the Presence of L-Dihydroxyphenylalanine
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Fungi"
DOI: 10.3390/jof6040328
Abstract: Species of the genus Paracoccidioides cause a systemic infection in human patients. Yeast cells of Paracoccidioides spp. produce melanin in the presence of L-dihydroxyphenylalanine and during infection, which may impact the pathogen’s survival in the… read more here.
Keywords: presence dihydroxyphenylalanine; yeast cells; paracoccidioides lutzii; lutzii yeast ... See more keywords