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   Articles with "paracrine" as a keyword



Periodontal ligament-derived mesenchymal stem cells modulate neutrophil responses via paracrine mechanisms.

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recommendations! Published in 2019 at "Journal of periodontology"

DOI: 10.1002/jper.18-0220

Abstract: BACKGROUND Mesenchymal stem cells differentiate into distinct mesenchymal cell lineages and regulate the immune response. The aim of this study was to determine whether periodontal ligament-derived mesenchymal stem cells (PDLSCs) have the ability to modulate… read more here.

Keywords: periodontal ligament; mesenchymal stem; stem cells; paracrine ... See more keywords

Liver heterotopia in the head of a patient with osteosarcoma of the maxilla. A paracrine tumor-induced hepatogenesis?

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recommendations! Published in 2017 at "Human pathology"

DOI: 10.1016/j.humpath.2016.08.008

Abstract: Heterotopia of liver tissue is uncommon. It has been reported at various sites, more frequently near the orthotopic liver, including gallbladder, hepatic ligaments, omentum, and retroperitoneum, rarely within the diaphragm and the thoracic cavity, and… read more here.

Keywords: head; osteosarcoma; liver heterotopia; liver ... See more keywords

Cold atmospheric plasma (CAP) activates angiogenesis-related molecules in skin keratinocytes, fibroblasts and endothelial cells and improves wound angiogenesis in an autocrine and paracrine mode.

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recommendations! Published in 2018 at "Journal of dermatological science"

DOI: 10.1016/j.jdermsci.2017.11.008

Abstract: BACKGROUND Cold atmospheric plasma (CAP) emerged as a novel therapeutic field with applications developed for bacterial sterilization, wound healing and cancer treatment. For clinical implementation it is important to know how CAP works and which… read more here.

Keywords: plasma; angiogenesis; cold atmospheric; paracrine ... See more keywords

Mimicking Paracrine TGFβ1 Signals during Myofibroblast Differentiation in 3D Collagen Networks

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-05912-x

Abstract: TGFβ1 is a key regulator for induction of tissue remodeling after dermal wounding. We present a model of paracrine delivery of TGFβ1 for differentiation of dermal fibroblasts based on a fibrillar 3D collagen matrix and… read more here.

Keywords: collagen; mimicking paracrine; tgf; paracrine ... See more keywords

Endothelial cell-cardiomyocyte cross-talk: understanding bidirectional paracrine signaling in cardiovascular homeostasis and disease.

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recommendations! Published in 2024 at "Clinical science"

DOI: 10.1042/cs20241084

Abstract: To maintain homeostasis in the heart, endothelial cells and cardiomyocytes engage in dynamic cross-talk through paracrine signals that regulate both cardiac development and function. Here, we review the paracrine signals that endothelial cells release to… read more here.

Keywords: disease; cross talk; paracrine; homeostasis ... See more keywords

Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upregulating MMPs in Mesangial Cells

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recommendations! Published in 2020 at "Journal of Diabetes Research"

DOI: 10.1155/2020/3847171

Abstract: Transplantation of umbilical cord mesenchymal stem cells (UC-MSCs) is currently considered a novel therapeutic strategy for diabetic nephropathy (DN). However, the mechanisms by which UC-MSCs ameliorate renal fibrosis in DN are not well understood. Herein,… read more here.

Keywords: cell proliferation; paracrine; cell; renal fibrosis ... See more keywords

Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis.

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recommendations! Published in 2018 at "Cancer research"

DOI: 10.1158/0008-5472.can-17-2316

Abstract: Inhibin is a heterodimeric TGFβ family ligand that is expressed in many cancers and is a selective biomarker for ovarian cancers; however, its tumor-specific functions remain unknown. Here, we demonstrate that the α subunit of… read more here.

Keywords: angiogenesis; inhibin novel; inhibin; metastasis ... See more keywords

Abstract B007: Therapy-associated paracrine signaling alters the cell states in Rhabdomyosarcoma

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recommendations! Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.pediatric25-b007

Abstract: Fusion-negative rhabdomyosarcoma (FN-RMS) is a childhood muscle cancer where relapse and refractory disease leads to poor outcomes. Our group has recently shown that FN-RMS is a cancer stem cell (CSC) disease and that these CD44+/CD90+/EGFR+… read more here.

Keywords: cancer; paracrine; therapy; cscs ... See more keywords

Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling

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recommendations! Published in 2018 at "Circulation Research"

DOI: 10.1161/circresaha.117.311589

Abstract: Cardiac excitation–contraction coupling (ECC) is the orchestrated process of initial myocyte electrical excitation, which leads to calcium entry, intracellular trafficking, and subsequent sarcomere shortening and myofibrillar contraction. Neurohumoral &bgr;-adrenergic signaling is a well-established mediator of… read more here.

Keywords: excitation contraction; paracrine; biology; cardiac excitation ... See more keywords

Novel stress granule-like structures are induced via a paracrine mechanism during viral infection

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recommendations! Published in 2022 at "Journal of Cell Science"

DOI: 10.1242/jcs.259194

Abstract: ABSTRACT To rapidly adapt to stresses such as infections, cells have evolved several mechanisms, which include the activation of stress response pathways and the innate immune response. These stress responses result in the rapid inhibition… read more here.

Keywords: novel stress; stress; stress granule; paracrine ... See more keywords

GPCRs in Autocrine and Paracrine Regulations

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recommendations! Published in 2019 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2019.00428

Abstract: G protein-coupled receptors (GPCRs) constitute the largest superfamily of integral membrane protein receptors. As signal detectors, the several 100 known GPCRs are responsible for sensing the plethora of endogenous ligands that are critical for the… read more here.

Keywords: paracrine regulations; paracrine; autocrine paracrine; cell ... See more keywords