Management of pheochromocytomas and paragangliomas: Review of current diagnosis and treatment options.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6010
Abstract: Pheochromocytomas (PCCs) are rare neuroendocrine tumors derived from the chromaffin cells of the adrenal medulla. When these tumors have an extra-adrenal location, they are called paragangliomas (PGLs) and arise from sympathetic and parasympathetic ganglia, particularly… read more here.
Keywords: review; pccs pgls; diagnosis treatment; paragangliomas ... See more keywords
Treatment and outcomes in pheochromocytomas and paragangliomas: a study of 110 cases from a single center
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1734-x
Abstract: PurposeMany pheochromocytomas and paragangliomas (PPGLs) are nowadays diagnosed as incidentalomas or by screening. This may have changed outcomes.MethodsWe reviewed 110 consecutive cases of PPGLs. Two cases with concurrent ectopic ACTH-syndrome were excluded.ResultsSixty-five percent had presented… read more here.
Keywords: surgery; treatment outcomes; outcomes pheochromocytomas; pheochromocytomas paragangliomas ... See more keywords
Protontherapy of head and neck paragangliomas: A monocentric study.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique"
DOI: 10.1016/j.canrad.2017.07.049
Abstract: PURPOSE The aim of this study was to assess efficacy and safety of proton beam therapy of paragangliomas of the head and neck, rare benign tumours developed close to crucial structures such as cranial nerves… read more here.
Keywords: therapy; study; paragangliomas; head neck ... See more keywords
Examination of PHOX2B in adult neuroendocrine neoplasms reveals relatively frequent expression in phaeochromocytomas and paragangliomas
Sign Up to like & getrecommendations! Published in 2017 at "Histopathology"
DOI: 10.1111/his.13243
Abstract: Paired‐like homeobox 2b (PHOX2B) is a transcription factor with expression outside of the central nervous system restricted to neurons and chromaffin cells of the autonomic nervous system. Germline mutations cause congenital central hypoventilation syndrome and… read more here.
Keywords: phaeochromocytomas paragangliomas; nervous system; paragangliomas; expression ... See more keywords
Intracranial paragangliomas versus schwannomas: Role of dynamic susceptibility contrast perfusion and diffusion MRI
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroimaging"
DOI: 10.1111/jon.13002
Abstract: Differentiating paragangliomas from schwannomas and distinguishing sporadic from neurofibromatosis type 2 (NF 2)‐related schwannomas is challenging but clinically important. This study aimed to assess the utility of dynamic susceptibility contrast perfusion MRI (DSC‐MRI) and diffusion‐weighted… read more here.
Keywords: paragangliomas; contrast perfusion; susceptibility contrast; dynamic susceptibility ... See more keywords
Novel potential causative genes in carotid paragangliomas
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DOI: 10.1186/s12881-019-0770-6
Abstract: BackgroundCarotid paragangliomas (CPGLs) are rare neuroendocrine tumors that arise from the paraganglion at the bifurcation of the carotid artery and are responsible for approximately 65% of all head and neck paragangliomas. CPGLs can occur sporadically… read more here.
Keywords: novel potential; causative genes; paragangliomas; cpgls ... See more keywords
Perioperative Management of Pheochromocytomas and Sympathetic Paragangliomas
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DOI: 10.1210/jendso/bvac004
Abstract: Abstract Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors arising from chromaffin cells of the adrenal medulla or extra-adrenal paraganglia, respectively. PPGLs have the highest degree of heritability among endocrine tumors. Currently, ~40% of individuals… read more here.
Keywords: sympathetic paragangliomas; perioperative management; paragangliomas; pheochromocytomas sympathetic ... See more keywords
Lenvatinib as a Therapeutic Option in Unresectable Metastatic Pheochromocytoma and Paragangliomas
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DOI: 10.1210/jendso/bvac044
Abstract: Abstract Context Metastatic pheochromocytomas and paragangliomas (mPPGL) are rare vascular neuroendocrine tumors that highly express vascular growth factors. Systemic treatment options in cases of unresectable multisite disease are limited. Multikinase inhibitors that inhibit angiogenesis, such… read more here.
Keywords: disease; paragangliomas; therapeutic option; treatment ... See more keywords
SUN-LB060 Paraganglioma in Pregnancy: Challenges to Treatment
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DOI: 10.1210/js.2019-sun-lb060
Abstract: Abstract Background: Paragangliomas are rare neuroendocrine tumors that arise from extra-adrenal chromaffin cells derived from the embryonic neural crest. Sympathetic paragangliomas secrete catecholamines and present with episodic hypertension and tachycardia. Paragangliomas in pregnancy are extremely… read more here.
Keywords: genetic testing; sun lb060; paraganglioma pregnancy; paragangliomas ... See more keywords
Predictors of outcome in phaeochromocytomas and paragangliomas
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DOI: 10.12688/f1000research.12419.1
Abstract: Phaeochromocytomas and paragangliomas (PPGLs) are catecholamine-secreting neuroendocrine tumours characterised by high rates of heritability and genetic heterogeneity. Despite advances in the genetic diagnosis and improved understanding of the molecular aberrations underlying these tumours, predictive markers… read more here.
Keywords: predictors outcome; paragangliomas; outcome phaeochromocytomas; phaeochromocytomas paragangliomas ... See more keywords
Paragangliomas da Cabeça e Pescoço: A Experiência de um Centro Oncológico do Sul da Europa.
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DOI: 10.20344/amp.17185
Abstract: INTRODUCTION Paragangliomas are usually benign slow-growing tumors, but they are locally invasive and can cause significant morbidity. The aim of this study was to characterize the presenting symptoms, secretory status, genetics, imaging features, treatment modalities,… read more here.
Keywords: head neck; neck paragangliomas; paragangliomas; pesco experi ... See more keywords