The m6 A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced science"
DOI: 10.1002/advs.202101329
Abstract: Messenger RNA m6 A modification is shown to regulate local translation in axons. However, how the m6 A codes in axonal mRNAs are read and decoded by the m6 A reader proteins is still unknown.… read more here.
Keywords: local translation; parallel fiber; readers ythdf1; ythdf1 ythdf2 ... See more keywords
Activity‐dependent plasticity of presynaptic GABAB receptors at parallel fiber synapses
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DOI: 10.1002/syn.22027
Abstract: Parallel fiber synapses in the cerebellum express a wide range of presynaptic receptors. However, presynaptic receptor expression at individual parallel fiber synapses is quite heterogeneous, suggesting physiological mechanisms regulate presynaptic receptor expression. We investigated changes… read more here.
Keywords: parallel fiber; fiber synapses; presynaptic gabab; receptor ... See more keywords
NMDARs in granule cells contribute to parallel fiber–Purkinje cell synaptic plasticity and motor learning
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2102635118
Abstract: Significance Learning depends on synaptic plasticity. The signaling mechanisms that control induction of plasticity determine the learning rules at the specific synapse involved. Moreover, the relationship between the activity patterns of synaptic inputs and the… read more here.
Keywords: parallel fiber; motor learning; synaptic plasticity; plasticity ... See more keywords
Ultrastructural effects of sleep and wake on the parallel fiber synapses of the cerebellum
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DOI: 10.1101/2022.10.31.514498
Abstract: Multiple evidence in rodents shows that the strength of excitatory synapses in the cerebral cortex and hippocampus is greater after wake than after sleep. The widespread synaptic weakening afforded by sleep is believed to keep… read more here.
Keywords: branched synapses; sleep wake; wake; parallel fiber ... See more keywords
ASSESSMENT OF TESTING PROTOCOLS FOR BAMBOO FOR TENSION PARALLEL TO FIBER
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Geomate"
DOI: 10.21660/2020.74.9207
Abstract: To determine tension parallel to fiber properties of Bamboo, one can employ ISO 22157. However, several studies highlighted some challenges in using the method such as premature failure of testing due to force at clamping… read more here.
Keywords: tensile strength; tension parallel; astm d143; parallel fiber ... See more keywords
Rack1 Controls Parallel Fiber–Purkinje Cell Synaptogenesis and Synaptic Transmission
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DOI: 10.3389/fncel.2019.00539
Abstract: Purkinje cells (PCs) in the cerebellum receive two excitatory afferents including granule cells-derived parallel fiber (PF) and the climbing fiber. Scaffolding protein Rack1 is highly expressed in the cerebellar PCs. Here, we found delayed formation… read more here.
Keywords: rack1; parallel fiber; fiber; rack1 controls ... See more keywords
Deletion of Calsyntenin-3, an atypical cadherin, suppresses inhibitory synapses but increases excitatory parallel-fiber synapses in cerebellum
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DOI: 10.7554/elife.70664
Abstract: Cadherins contribute to the organization of nearly all tissues, but the functions of several evolutionarily conserved cadherins, including those of calsyntenins, remain enigmatic. Puzzlingly, two distinct, non-overlapping functions for calsyntenins were proposed: As postsynaptic neurexin… read more here.
Keywords: parallel fiber; fiber synapses; fiber; excitatory parallel ... See more keywords