MODELING OF LAMPREY RETICULOSPINAL NEURONS: MULTIPLE DISTINCT PARAMETER SETS YIELD REALISTIC SIMULATIONS.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neurophysiology"
DOI: 10.1152/jn.00070.2020
Abstract: For the lamprey and other vertebrates, reticulospinal (RS) neurons project descending axons to the spinal cord and activate motor networks to initiate locomotion and other behaviors. In the present study, a biophysically-detailed computer model of… read more here.
Keywords: lamprey reticulospinal; parameter sets; reticulospinal neurons; modeling lamprey ... See more keywords
Assessing the effect of forcefield parameter sets on the accuracy of relative binding free energy calculations
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.972162
Abstract: Software for accurate prediction of protein-ligand binding affinity can be a key enabling tool for small molecule drug discovery. Free energy perturbation (FEP) is a computational technique that can be used to compute binding affinity… read more here.
Keywords: assessing effect; energy; free energy; effect forcefield ... See more keywords
Empirical and Computational Evaluation of Hemolysis in a Microfluidic Extracorporeal Membrane Oxygenator Prototype
Sign Up to like & getrecommendations! Published in 2024 at "Micromachines"
DOI: 10.3390/mi15060790
Abstract: Microfluidic devices promise to overcome the limitations of conventional hemodialysis and oxygenation technologies by incorporating novel membranes with ultra-high permeability into portable devices with low blood volume. However, the characteristically small dimensions of these devices… read more here.
Keywords: hemolysis; parameter sets; microfluidic devices; blood ... See more keywords