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   Articles with "paraplegia type" as a keyword



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Characteristics of serum neurofilament light chain as a biomarker in hereditary spastic paraplegia type 4

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recommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.51518

Abstract: While the anticipated rise of disease‐modifying therapies calls for reliable trial outcome parameters, fluid biomarkers are lacking in spastic paraplegia type 4 (SPG4), the most prevalent form of hereditary spastic paraplegia. We therefore investigated serum… read more here.

Keywords: spastic paraplegia; neurofilament light; paraplegia; hereditary spastic ... See more keywords
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Specific Gait Changes in Prodromal Hereditary Spastic Paraplegia Type 4: preSPG4 Study

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recommendations! Published in 2022 at "Movement Disorders"

DOI: 10.1002/mds.29199

Abstract: In hereditary spastic paraplegia type 4 (SPG4), subclinical gait changes might occur years before patients realize gait disturbances. The prodromal phase of neurodegenerative disease is of particular interest to halt disease progression by future interventions… read more here.

Keywords: spastic paraplegia; hereditary spastic; paraplegia type; gait changes ... See more keywords
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Generation of induced pluripotent stem cell line (ZZUi030-A) from a patient with spastic paraplegia type 7.

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recommendations! Published in 2021 at "Stem cell research"

DOI: 10.1016/j.scr.2021.102525

Abstract: Spastic paraplegia type 7 is a rare and classical monogenic inherited neurodegenerative disease caused by heterozygous mutations in the SPG7 gene. The principle clinical features include progressive spasms of the lower limbs, scissor gait, and… read more here.

Keywords: paraplegia type; stem cell; spastic paraplegia; pluripotent stem ... See more keywords
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Spastic Paraplegia Type 8: A First Report from India

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recommendations! Published in 2023 at "Annals of Indian Academy of Neurology"

DOI: 10.4103/aian.aian_901_22

Abstract: Dear Sir, Spastic paraplegia type 8 (SPG8) is a rare autosomal‐dominant hereditary spastic paraplegia (AD‐HSP) caused by the mutation in the WASHC5 (KIAA0196) gene on chromosome 8. Patients with SPG8 commonly present with progressive lower… read more here.

Keywords: limb spasticity; spastic paraplegia; paraplegia; paraplegia type ... See more keywords