Sodium Selenite Prevents Paraquat-Induced Neurotoxicity in Zebrafish
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0441-6
Abstract: Considering the antioxidant properties of sodium selenite (Na2SeO3) and the involvement of oxidative stress events in paraquat-induced neurotoxicity, this study investigated the protective effect of dietary Na2SeO3 on biochemical and behavioral parameters of zebrafish exposed… read more here.
Keywords: induced neurotoxicity; na2seo3 prevented; prevented increase; paraquat induced ... See more keywords
HSPB5 (αB-crystallin) confers protection against paraquat-induced oxidative stress at the organismal level in a tissue-dependent manner
Sign Up to like & getrecommendations! Published in 2020 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-020-01171-4
Abstract: Oxidative stress is one of the major and continuous stresses, an organism encounters during its lifetime. Tissues such as the brain, liver and muscles are more prone to damage by oxidative stress due to their… read more here.
Keywords: protection; induced oxidative; stress; paraquat induced ... See more keywords
Atorvastatin protected from paraquat-induced cytotoxicity in alveolar macrophages via down-regulation of TLR-4.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2016.11.011
Abstract: The current study designed to clarify the mechanism of paraquat-induced cytotoxicity and protective effects of Atorvastatin on freshly isolated alveolar macrophages (AMs). AMs were collected via bronchoalveolar lavage and exposed to various concentrations of paraquat… read more here.
Keywords: alveolar macrophages; paraquat; tlr; induced cytotoxicity ... See more keywords
Protective effects of febuxostat against paraquat‐induced lung toxicity in rats: Impact on RAGE/PI3K/Akt pathway and downstream inflammatory cascades
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2019.02.007
Abstract: Aims: The herbicide paraquat causes fatal lung toxicity by induction of xanthine oxidase, production of free radicals and inflammation. Febuxostat, a xanthine oxidase inhibitor and anti‐gout has recently shown anti‐inflammatory activity. Accordingly, this study was… read more here.
Keywords: paraquat; pi3k akt; induced lung; paraquat induced ... See more keywords
TLR3 is involved in paraquat‐induced acute renal injury
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2019.03.029
Abstract: Aims To investigate the role of Toll‐like receptor 3 (TLR3) in mouse paraquat‐induced acute renal injury. Materials and methods Acute renal injury was established in C57BL/6J mice by intraperitoneal injection of paraquat (28 mg/kg). The… read more here.
Keywords: paraquat; renal tissues; acute renal; renal injury ... See more keywords
Cromolyn Sodium Attenuates Paraquat-Induced Lung Injury by Modulation of Proinflammatory Cytokines.
Sign Up to like & getrecommendations! Published in 2017 at "Drug research"
DOI: 10.1055/s-0042-123711
Abstract: The current study aimed to investigate the effects of Cromolyn Sodium (CS) on proinflammatory cytokines in Paraquat (PQ)-induced lung damage in rat. Animals were randomly divided into 5 groups. Group 1 and 2 received nebulized… read more here.
Keywords: proinflammatory cytokines; cromolyn sodium; induced lung; paraquat induced ... See more keywords
The Ameliorative Effects of Allopurinol on Paraquat-Induced Pulmonary Fibrosis in Rats
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Sciences"
DOI: 10.15171/ps.2019.2
Abstract: Background: Pulmonary fibrosis is described as a chronic idiopathic inflammatory disease of the interstitial lungs. It is associated with a potentially fatal prognosis, and patients show insignificant response to treatment. To treat paraquat (PQ)-induced pulmonary… read more here.
Keywords: fibrosis; pulmonary fibrosis; paraquat induced; effects allopurinol ... See more keywords
Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.64164.14128
Abstract: Objective(s): The goal of this study was to evaluate the neuroprotective effects of vit B12 on paraquat-induced neurotoxicity. Materials and Methods: Thirty-six male mice were randomly divided into six groups. Three groups were treated intraperitoneally… read more here.
Keywords: b12 paraquat; paraquat induced; vit b12; b12 ... See more keywords
Combined Ubisol-Q10 and Ashwagandha Root Extract Target Multiple Biochemical Mechanisms and Reduces Neurodegeneration in a Paraquat-Induced Rat Model of Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10040563
Abstract: Parkinson’s disease (PD) is characterized by progressive neurodegeneration in the substantia nigra (SN) region resulting in loss of movement coordination. Current therapies only provide symptomatic relief, and there is no agent to halt the progression… read more here.
Keywords: induced rat; treatment; ubisol q10; parkinson disease ... See more keywords
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu15010198
Abstract: Endogenous glutathione (GSH) effectively regulates redox homeostasis in the body. This study aimed to investigate the regulatory mechanism of different dietary levels of GSH supplementation on the intestinal barrier and antioxidant function in a paraquat-induced… read more here.
Keywords: stress; barrier antioxidant; intestinal barrier; oxidative stress ... See more keywords
Protection against Paraquat-Induced Oxidative Stress by Curcuma longa Extract-Loaded Polymeric Nanoparticles in Zebrafish Embryos
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14183773
Abstract: The link between oxidative stress and environmental factors plays an important role in chronic degenerative diseases; therefore, exogenous antioxidants could be an effective alternative to combat disease progression and/or most significant symptoms. Curcuma longa L.… read more here.
Keywords: curcuma longa; paraquat; oxidative stress; zebrafish embryos ... See more keywords