Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity.
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DOI: 10.1016/j.bioorg.2021.105359
Abstract: Malaria is a devastating disease caused by Plasmodium parasites. Emerging resistance against current antimalarial therapeutics has engendered the need to develop antimalarials with novel structural classes. We recently described the identification and initial optimization of… read more here.
Keywords: class; asexual parasite; parasite activity; fast acting ... See more keywords