Resistance to Haemonchus contortus in Corriedale sheep is associated to high parasite-specific IgA titer and a systemic Th2 immune response
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-55447-6
Abstract: Gastrointestinal nematode infections, including Haemonchus contortus, are one of the main causes of economic losses to ovine farmers worldwide. In order to contribute to the control of nematode infections and avoid parasite spreading we generated… read more here.
Keywords: response; resistance; immune response; parasite specific ... See more keywords
Convergent evolution of a genotoxic stress response in a parasite-specific p53 homolog
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2205201119
Abstract: Significance P53 is an important tumor suppressor that is found throughout metazoans, including invertebrates that do not develop malignancies. The prevailing theory for why these invertebrates possess a tumor suppressor is that P53 originally evolved… read more here.
Keywords: convergent evolution; parasite specific; p53; genotoxic stress ... See more keywords