Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13398
Abstract: Parathyroid carcinoma (PC) is an ultra-rare malignancy with a high risk of recurrence after surgery. Tumor-directed systemic treatments for PC are not established. We used whole-genome and RNA sequencing in four patients with advanced PC… read more here.
Keywords: targeted therapy; advanced parathyroid; parathyroid carcinoma; therapy advanced ... See more keywords
Intrapericardial parathyroid carcinoma: a case report
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine"
DOI: 10.1007/s12020-020-02283-8
Abstract: Purpose Ectopic parathyroid glands are thought to be the cause of a significant portion of failed primary surgery for hyperparathyroidism. Parathyroid carcinoma (PTCA) is a rare malignant tumor, and ectopic PTCA is a particularly unusual… read more here.
Keywords: intrapericardial parathyroid; ptca; parathyroid carcinoma; parathyroid ... See more keywords
The significance of an immunohistochemical marker-based panel in assisting the diagnosis of parathyroid carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Endocrine"
DOI: 10.1007/s12020-024-03687-6
Abstract: Parathyroid carcinoma (PC) is an endocrine malignancy with a poor prognosis. However, the diagnosis of PC is still a difficult problem. A model with immunohistochemical (IHC) staining of 5 biomarkers has been reported from limited… read more here.
Keywords: diagnosis; ihc; panel; parafibromin ... See more keywords
Giant parathyroid carcinoma: Diagnostic, difficulties and therapeutic strategies: A case report
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2021.102919
Abstract: Introduction Parathyroid carcinoma is a very aggressive malignant tumor. It is mostly revealed by clinical primary hyperparathyroidism. Case presentation We report a rare case of parathyroid carcinoma in a 61-year-old-male patient who presented with a… read more here.
Keywords: carcinoma; primary hyperparathyroidism; parathyroid carcinoma; case ... See more keywords
Parathyroid Carcinoma and Ectopic Secretion of Parathyroid hormone.
Sign Up to like & getrecommendations! Published in 2021 at "Endocrinology and metabolism clinics of North America"
DOI: 10.1016/j.ecl.2021.07.001
Abstract: The most common causes of hypercalcemia are primary hyperparathyroidism (PHPT) and malignancy. Parathyroid carcinoma (PC), causing a severe PHPT, is the rarest parathyroid tumor. A diagnosis of PC is challenging because the clinical profile overlaps… read more here.
Keywords: parathyroid hormone; parathyroid carcinoma; secretion; parathyroid ... See more keywords
Case report of parathyroid carcinoma in a pediatric patient.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pediatric otorhinolaryngology"
DOI: 10.1016/j.ijporl.2019.06.003
Abstract: Parathyroid carcinoma is extremely rare in pediatric population. The authors report a case of 15-year-old girl with extremely elevated serum calcium (4.1 mmol/L) and parathyroid hormone (1170 pg/mL), with palpable neck mass. After en bloc… read more here.
Keywords: carcinoma; case report; parathyroid carcinoma; patient ... See more keywords
Prognostic Scoring System to Risk Stratify Parathyroid Carcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Surgeons"
DOI: 10.1016/j.jamcollsurg.2017.01.060
Abstract: BACKGROUND Parathyroid carcinoma is a rare endocrine malignancy that lacks an established system for risk categorization. This study evaluated a prognostic scoring system for recurrence-free survival (RFS) of patients with parathyroid carcinoma. STUDY DESIGN Patients… read more here.
Keywords: system; scoring system; parathyroid carcinoma; rfs ... See more keywords
Parathyroid carcinoma and atypical parathyroid tumor: Analysis of an Italian database.
Sign Up to like & getrecommendations! Published in 2024 at "European journal of endocrinology"
DOI: 10.1093/ejendo/lvae121
Abstract: OBJECTIVE Atypical parathyroid tumor (aPT) and parathyroid carcinoma (PC) are extremely rare parathyroid neoplasms, accounting together for less than 2% of all parathyroid tumors. They often present an overlapping clinical phenotype, sharing clinical, biochemical, and… read more here.
Keywords: atypical parathyroid; parathyroid; parathyroid carcinoma; endocrinology ... See more keywords
Hyperparathyroidism Due to Concurrent Parathyroid Carcinoma and Parathyroid Adenoma.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Nuclear Medicine"
DOI: 10.1097/rlu.0000000000002755
Abstract: Parathyroid carcinoma is uncommon, and its coexistence with parathyroid adenoma is extremely rare. A 28-year-old woman with hyperparathyroidism underwent dual-phase Tc-sestamibi SPECT/CT scan for presurgical evaluation. The images showed intense activity inside the left side… read more here.
Keywords: parathyroid adenoma; parathyroid; hyperparathyroidism; parathyroid carcinoma ... See more keywords
Parathyroid Carcinoma With Marked Uptake of 99mTcO4.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Nuclear Medicine"
DOI: 10.1097/rlu.0000000000003448
Abstract: A 51-year-old man with a palpable neck mass and elevated parathyroid hormone was referred to our department for parathyroid scintigraphy. After injection of 740 MBq Tc-MIBI, a dual-phase scan was obtained, which revealed a persistent… read more here.
Keywords: carcinoma marked; carcinoma; marked uptake; mass ... See more keywords
Hyperparathyroidism Caused by Coexisting Parathyroid Hyperplasia and Unilateral Bifocal Parathyroid Carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004343
Abstract: ABSTRACT The coexistence of parathyroid hyperplasia and carcinoma is uncommon. Here we report findings of 99mTc-sestamibi SPECT/CT study in a case of unilateral bifocal parathyroid carcinoma coexisting with parathyroid hyperplasia in a 49-year-old man. The… read more here.
Keywords: bifocal parathyroid; parathyroid hyperplasia; parathyroid; parathyroid carcinoma ... See more keywords