Effects of FGF‐23‐mediated ERK/MAPK signaling pathway on parathyroid hormone secretion of parathyroid cells in rats with secondary hyperparathyroidism
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DOI: 10.1002/jcp.26525
Abstract: This study is supposed to investigate the effect of FGF‐23 on parathyroid hormone (PTH) secretion through ERK/MAPK signaling pathway in secondary hyperparathyroidism (SHPT) rat model. Thirty rats were equally served as the normal and SHPT… read more here.
Keywords: protein; fgf; secretion; parathyroid cells ... See more keywords
Excessive proliferation and apoptosis of parathyroid cells contribute to primary hyperparathyroidism in rabbit model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Investigative Medicine"
DOI: 10.1136/jim-2021-002184
Abstract: To explore the molecular pathogenesis of primary hyperparathyroidism (PHPT), we investigated the proliferation and apoptosis of parathyroid cells in a rabbit model of diet-induced PHPT. A total of 120 adult Chinese rabbits were randomly divided… read more here.
Keywords: parathyroid; group; parathyroid cells; proliferation apoptosis ... See more keywords
Development and application of primary rat parathyroid cells for transplantation in hypoparathyroidism
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DOI: 10.21037/gs-24-411
Abstract: Background Hypoparathyroidism (HPO) is characterized by deficient secretion of parathyroid hormone (PTH), leading to hypocalcemia and disrupted calcium homeostasis. Current treatments rely on calcium and vitamin D supplementation, which do not adequately mimic physiological PTH… read more here.
Keywords: primary rat; rat parathyroid; culture; parathyroid ... See more keywords
Mechanism of calcitriol regulating parathyroid cells in secondary hyperparathyroidism
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1020858
Abstract: A common consequence of chronic renal disease is secondary hyperparathyroidism (SHPT) and is closely related to the mortality and morbidity of uremia patients. Secondary hyperparathyroidism (SHPT) is caused by excessive PTH production and release, as… read more here.
Keywords: cell proliferation; parathyroid cells; cells secondary; secondary hyperparathyroidism ... See more keywords