Altération de la réparation de l’ADN et cancer
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DOI: 10.1016/j.bulcan.2017.09.006
Abstract: Maintaining the genetic integrity is a key process in cell viability and is enabled by a wide network of repair pathways. When this system is defective, it generates genomic instability and results in an accumulation… read more here.
Keywords: ration paration; alt ration; cancer alt; paration adn ... See more keywords
Anomalies de la réparation de l’ADN et cancers gynécologiques
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DOI: 10.1016/j.bulcan.2017.09.007
Abstract: Resume L’activite des inhibiteurs de poly-ADP ribose polymerase (iPARP) dans les cancers de l’ovaire BRCA mutes a apporte la premiere demonstration du concept de letalite synthetique. De nombreuses etudes precliniques et cliniques ont demontre qu’une… read more here.
Keywords: anomalies paration; paration adn; cancers gyn; adn cancers ... See more keywords