Sex and age influence gonadal steroid hormone receptor distributions relative to estrogen receptor β‐containing neurons in the mouse hypothalamic paraventricular nucleus
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25093
Abstract: Within the hypothalamic paraventricular nucleus (PVN), estrogen receptor (ER) β and other gonadal hormone receptors play a role in central cardiovascular processes. However, the influence of sex and age on the cellular and subcellular relationships… read more here.
Keywords: hormone; hypothalamic paraventricular; paraventricular nucleus; receptor ... See more keywords
Uncovering the brain‐wide pattern of synaptic input to vasopressin‐expressing neurons in the paraventricular nucleus of the hypothalamus
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25476
Abstract: Arginine vasopressin (AVP) is a neuropeptide critical for the mammalian stress response and social behavior. AVP produced in the hypothalamus regulates water osmolality and vasoconstriction in the body, and in the brain, it regulates social… read more here.
Keywords: vasopressin; brain; expressing neurons; social behavior ... See more keywords
In the parvocellular part of paraventricular nucleus, glutamatergic and GABAergic neurons mediate cardiovascular responses to AngII
Sign Up to like & getrecommendations! Published in 2022 at "Synapse"
DOI: 10.1002/syn.22259
Abstract: Angiotensinergic, GABAergic, and glutamatergic neurons are present in the parvocellular region of the paraventricular nucleus (PVNp). It has been shown that microinjection of AngII into the PVNp increases arterial pressure (AP) and heart rate (HR).… read more here.
Keywords: part paraventricular; paraventricular nucleus; parvocellular part; glutamatergic gabaergic ... See more keywords
Incubation of feeding behavior is regulated by neuromedin U receptor 2 in the paraventricular nucleus of the hypothalamus
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.08.015
Abstract: Abstract A diet of energy‐dense food, characterized mainly as a high‐fat diet, leads to a persistent excessive consumption defined as overeating. According to the National Institute of Health, more than 2 in 3 adults in… read more here.
Keywords: incubation; paraventricular nucleus; neuromedin receptor; high fat ... See more keywords
Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2022.03.084
Abstract: BACKGROUND Hypertension can be attributed to increased sympathetic activities. Presympathetic neurons in the paraventricular nucleus (PVN) of the hypothalamus are capable of modulating sympathetic outflow, thus contributing to the pathogenesis of neurogenic hypertension. Epoxyeicosatrienoic acids… read more here.
Keywords: expression; paraventricular nucleus; eet; hypertensive rats ... See more keywords
Prepubertal and adult male rats differ in the degree and pattern of stress reactive neurons in brain regions that project to the paraventricular nucleus of the hypothalamus
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research"
DOI: 10.1016/j.brainres.2021.147371
Abstract: The hormonal stress response, mediated by the hypothalamic-pituitary-adrenal (HPA) axis, shows greater responsiveness to various stressors in prepubertal compared to adult animals. Though the implications of this age-related change are unclear, this heightened reactivity might… read more here.
Keywords: adult; male rats; paraventricular nucleus; stress ... See more keywords
Dedicated C-fiber vagal sensory afferent pathways to the paraventricular nucleus of the hypothalamus
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research"
DOI: 10.1016/j.brainres.2021.147625
Abstract: The nucleus of the solitary tract (NTS) receives viscerosensory information from the vagus nerve to regulate diverse homeostatic reflex functions. The NTS projects to a wide network of other brain regions, including the paraventricular nucleus… read more here.
Keywords: projecting nts; paraventricular nucleus; pvn projecting; nucleus hypothalamus ... See more keywords
Gαi/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109997
Abstract: The anorexigenic effect of serotonergic compounds has largely been attributed to activation of serotonin 2C receptors (Htr2cs). Using mouse genetic models in which Htr2c can be selectively deleted or restored (in Htr2c-null mice), we investigate… read more here.
Keywords: nucleus hypothalamus; paraventricular nucleus; serotonin; effect ... See more keywords
Mechanisms of orexin 2 receptor-mediated depolarization in the rat paraventricular nucleus of the hypothalamus.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172802
Abstract: The paraventricular nucleus of the hypothalamus (PVN) contains dense orexin 2 (OX2) receptor. We examined the mechanisms of OX2 receptor-mediated excitation on electrophysiologically identified type I (putative magnocellular), low-threshold spikes (LTS)-expressing type II (putative preautonomic),… read more here.
Keywords: ox2 receptor; paraventricular nucleus; conductance; type neurons ... See more keywords
Alpha adrenergic receptor signaling in the hypothalamic paraventricular nucleus is diminished by the chronic intermittent hypoxia model of sleep apnea
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2020.113517
Abstract: Chronic intermittent hypoxia (CIH) is a model for obstructive sleep apnea. The paraventricular nucleus (PVN) of the hypothalamus has been suggested to contribute to CIH-induced exaggerated cardiorespiratory reflexes, sympathoexcitation and hypertension. This may occur, in… read more here.
Keywords: cih; paraventricular nucleus; sleep apnea; intermittent hypoxia ... See more keywords
Endocannabinoid and nitric oxide systems of the hypothalamic paraventricular nucleus mediate effects of NPY on energy expenditure
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2018.08.007
Abstract: Objective Neuropeptide Y (NPY) is one of the most potent orexigenic peptides. The hypothalamic paraventricular nucleus (PVN) is a major locus where NPY exerts its effects on energy homeostasis. We investigated how NPY exerts its… read more here.
Keywords: energy expenditure; npy induced; energy; hypothalamic paraventricular ... See more keywords