O-Acetylation of Capsular Polysialic Acid Enables Escherichia coli K1 Escaping from Siglec-Mediated Innate Immunity and Lysosomal Degradation of E. coli-Containing Vacuoles in Macrophage-Like Cells
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DOI: 10.1128/spectrum.00399-21
Abstract: Escherichia coli K1 is a leading cause of neonatal meningitis. The mortality and morbidity of this disease remain significantly high despite antibiotic therapy. ABSTRACT Escherichia coli K1 causes bacteremia and meningitis in human neonates. The… read more here.
Keywords: parent strain; siglec; escherichia coli; psa ... See more keywords