The Mcm2-Ctf4-PolĪ± Axis Facilitates Parental Histone H3-H4 Transfer to Lagging Strands.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.09.001
Abstract: Although essential for epigenetic inheritance, the transfer of parental histone (H3-H4)2 tetramers that contain epigenetic modifications to replicating DNA strands is poorly understood. Here, we show that the Mcm2-Ctf4-PolĪ± axis facilitates the transfer of parental… read more here.
Keywords: strand; pol; parental histone; transfer ... See more keywords
Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc0330
Abstract: Parental histone dynamics at the replication fork are altered by free histones, leading to controlled eviction or transfer. During replication, nucleosomes are disrupted ahead of the replication fork, followed by their reassembly on daughter strands… read more here.
Keywords: replication fork; histone recycling; parental histone; replication ... See more keywords