Influence of validating the parental origin on the clinical interpretation of fetal copy number variations in 141 core family cases
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DOI: 10.1002/mgg3.944
Abstract: The sources and variants types of the copy number variations (CNVs) in prenatal fetal, and the critical role of parental origin on the interpretation of fetal CNVs are unclear. read more here.
Keywords: parental origin; copy number; number variations; interpretation fetal ... See more keywords
Karyotype Analysis, Genomic and Fluorescence In Situ Hybridization (GISH and FISH) Reveal the Ploidy and Parental Origin of Chromosomes in Paeonia Itoh Hybrids
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DOI: 10.3390/ijms231911406
Abstract: Itoh hybrids are intersectional hybrids in Paeonia L. with sect. Moutan and sect. Paeonia as paternal and maternal parents, respectively. Therefore, these hybrids have herbaceous stems with improved ornamental value introduced by the paternal parent.… read more here.
Keywords: karyotype analysis; itoh hybrids; origin chromosomes; parental origin ... See more keywords
Reassessment of weak parent-of-origin expression bias shows it rarely exists outside of known imprinted regions
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DOI: 10.7554/elife.83364
Abstract: In mouse and human, genes subjected to genomic imprinting have been shown to function in development, behavior, and post-natal adaptations. Failure to correctly imprint genes in human is associated with developmental syndromes, adaptive, and metabolic… read more here.
Keywords: known imprinted; origin; expression; expression bias ... See more keywords