Biologic profiles meet clinical priorities: incorporating pseudopyloric, and spasmolytic-expressing metaplasia in the assessment of gastric atrophy
Sign Up to like & getrecommendations! Published in 2020 at "Virchows Archiv"
DOI: 10.1007/s00428-020-02814-8
Abstract: The interesting study by Ryoji Kushima and coauthors [1] adds new insights to the clinicobiological profiling of the pseudopyloric (PPM) transformation of the natively oxyntic gastric glands. In particular, the design of the study deals… read more here.
Keywords: assessment gastric; study; parietal cells; oxyntic glands ... See more keywords
Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle.
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DOI: 10.1016/j.devcel.2017.04.003
Abstract: Gastric acid secretion by parietal cells requires trafficking and exocytosis of H/K-ATPase-rich tubulovesicles (TVs) toward apical membranes in response to histamine stimulation via cyclic AMP elevation. Here, we found that TRPML1 (ML1), a protein that… read more here.
Keywords: acid secretion; parietal cells; acid; gastric acid ... See more keywords
Parietal Cell Death by Cytokines
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2018.01.019
Abstract: arietal cell atrophy in the human stomach occurs Palong a continuum of gastric inflammation, atrophy, and then metaplasia, a preneoplastic lesion. In mice, and to a lesser extent in human beings, the best-characterized type of… read more here.
Keywords: parietal cell; parietal; parietal cells; atrophy ... See more keywords