Parkin deficiency perturbs striatal circuit dynamics
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DOI: 10.1016/j.nbd.2020.104737
Abstract: Loss-of-function mutations in the parkin-encoding PARK2 gene are a frequent cause of young-onset, autosomal recessive Parkinson's disease (PD). Parkin knockout mice have no nigro-striatal neuronal loss but exhibit abnormalities of striatal dopamine transmission and cortico-striatal… read more here.
Keywords: circuit dynamics; deficiency perturbs; parkin deficiency; circuit ... See more keywords