Parkin inhibits necroptosis to prevent cancer
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DOI: 10.1038/s41556-019-0350-1
Abstract: Loss-of-function mutations in the ubiquitin ligase Parkin are a cause of Parkinson’s disease. Parkin also has tumour-suppressor activity, although how Parkin prevents cancer is unclear. Unexpectedly, Parkin is found to suppress cancer by inhibiting an… read more here.
Keywords: parkin inhibits; inhibits necroptosis; biology; cancer ... See more keywords