Corrigendum: SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila.
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DOI: 10.1093/hmg/ddy408
Abstract: SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila Alessandra Zanon1,†, Sreehari Kalvakuri2,†, Aleksandar Rakovic3,†, Luisa Foco1, Marianna Guida1, Christine Schwienbacher1, Alice Serafin1, Franziska Rudolph3, Michaela Trilck3,… read more here.
Keywords: interacts parkin; neurology; mitochondria prevents; slp interacts ... See more keywords
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria
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DOI: 10.1098/rsob.210255
Abstract: Mutations in Parkin and PINK1 cause early-onset familial Parkinson's disease. Parkin is a RING-In-Between-RING E3 ligase that transfers ubiquitin from an E2 enzyme to a substrate in two steps: (i) thioester intermediate formation on Parkin… read more here.
Keywords: near pink1; selective localization; ubiquitination; parkin mitochondria ... See more keywords