Miro2 supplies a platform for Parkin translocation to damaged mitochondria
Sign Up to like & getrecommendations! Published in 2019 at "Science Bulletin"
DOI: 10.1016/j.scib.2019.04.033
Abstract: PINK1/Parkin-mediated mitophagy is an important process in selective removal of damaged mitochondria, in which translocation of Parkin to damaged mitochondria is recognized as an initiation step. At present, how the damaged mitochondria are selectively recognized… read more here.
Keywords: translocation; damaged mitochondria; supplies platform; parkin translocation ... See more keywords
SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-19102-2
Abstract: Mitophagy, the selective degradation of mitochondria by autophagy, is crucial for the maintenance of healthy mitochondrial pool in cells. The critical event in mitophagy is the translocation of cytosolic Parkin, a ubiquitin ligase, to the… read more here.
Keywords: parkin translocation; mitochondrial translocation; translocation; sesn2 ... See more keywords