LINC00667 regulates MPP+‐induced neuronal injury in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51480
Abstract: Parkinson’s disease (PD), also known as paralysis tremor, is a chronic disease of the central nervous system. It has been reported that hepatocyte nuclear factor 4 alpha (HNF4A) is upregulated in PD, but its specific… read more here.
Keywords: mpp induced; parkinson disease; linc00667 regulates; parkinson ... See more keywords
Epigenome‐wide association study, meta‐analysis, and multiscore profiling of whole blood in Parkinson's disease
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.52292
Abstract: An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation… read more here.
Keywords: epigenome wide; methylation; wide association; parkinson ... See more keywords
SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease (Adv. Sci. 17/2025)
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202570126
Abstract: New Pathological Mechanism of Parkinson's Disease In article number 2411235, Jie Xiang, Jie Zhang, Shengxi Wu, and colleagues employ a well‐known Chinese myth “Nezha's Rebellion in the Sea” to elucidate the neuroprotective role of SIRT3… read more here.
Keywords: sirt3 mediated; parkinson; parkinson disease; mediated deacetylation ... See more keywords
A Secretory Vesicle Failure in Parkinson's Disease Occurs in Human Platelets
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26335
Abstract: The presence of elevated dopamine (DA) and its major metabolites in the cytosol of neurons has been associated with their vulnerability in Parkinson's disease (PD). Over 99% of the cell's amines are confined to secretory… read more here.
Keywords: parkinson disease; secretory vesicle; failure parkinson; vesicle failure ... See more keywords
Prediction of Cognitive Heterogeneity in Parkinson's Disease: A 4‐Year Longitudinal Study Using Clinical, Neuroimaging, Biological and Electrophysiological Biomarkers
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Neurology"
DOI: 10.1002/ana.27035
Abstract: Cognitive impairment in Parkinson's disease (PD) can show a very heterogeneous trajectory among patients. Here, we explored the mechanisms involved in the expression and prediction of different cognitive phenotypes over 4 years. read more here.
Keywords: prediction cognitive; cognitive heterogeneity; parkinson; parkinson disease ... See more keywords
Neuroimmunomodulatory properties of DPSCs in an in vitro model of Parkinson's disease
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1655
Abstract: In neurodegenerative diseases, such as Alzheimer's and Parkinson's, microglial cell activation is thought to contribute to their degeneration by producing neurotoxic compounds. While dental pulp stem cells (DPSCs) have been regarded as the next possible… read more here.
Keywords: properties dpscs; vitro model; parkinson; neuroimmunomodulatory properties ... See more keywords
Comment on: Management of Parkinson's Disease During Pregnancy
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13048
Abstract: I read with interest the detailed literature review on the management of Parkinson’s disease during pregnancy by Young and colleagues. As the authors pointed out, there is a paucity of robust evidence to guide medication… read more here.
Keywords: parkinson; management parkinson; disease pregnancy; parkinson disease ... See more keywords
The Profound Impact of Gastrointestinal Stasis on Levodopa Response in Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13425
Abstract: Gastrointestinal involvement in Parkinson ’ s disease (PD) can impact quality of life through disabling symptoms including nausea, early satiety, anorexia, and constipation and via disruption of oral levodopa absorption and motor and nonmotor fl… read more here.
Keywords: profound impact; parkinson disease; gastrointestinal stasis; impact gastrointestinal ... See more keywords
Rating Scales for Medication Adherence in Parkinson's Disease: A Systematic Review for Critique and Recommendations
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13586
Abstract: Behaviors interfering with medication adherence (MA) are common and often complex in Parkinson's disease (PD), negatively affecting quality of life and undermining the value of clinical trials. The Clinical Outcome Assessments (COA) Scientific Evaluation Committee… read more here.
Keywords: parkinson; parkinson disease; medication adherence; rating scales ... See more keywords
Parkinson's Disease‐Cognitive Rating Scale (PD‐CRS): Normative Data and Mild Cognitive Impairment Assessment in Brazil
Sign Up to like & getrecommendations! Published in 2023 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13657
Abstract: The Parkinson's Disease‐Cognitive Rating Scale (PD‐CRS) assesses posterior‐cortical and frontal‐subcortical cognitive functioning and distinguishes mild cognitive impairment in Parkinson's disease (PD‐MCI); however, it was not evaluated in Brazil. read more here.
Keywords: disease cognitive; parkinson disease; cognitive rating; rating scale ... See more keywords
Quantifying Social Connectedness in Parkinson's Disease: Reliability and Validity of a Clinical Assessment Toolkit
Sign Up to like & getrecommendations! Published in 2024 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.14298
Abstract: Loneliness and isolation impact health detrimentally but are understudied in Parkinson's disease (PD). Outcome measurement properties for social connection remain unexplored in PD. read more here.
Keywords: social connectedness; connectedness parkinson; quantifying social; parkinson ... See more keywords