LINC00667 regulates MPP+‐induced neuronal injury in Parkinson’s disease
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DOI: 10.1002/acn3.51480
Abstract: Parkinson’s disease (PD), also known as paralysis tremor, is a chronic disease of the central nervous system. It has been reported that hepatocyte nuclear factor 4 alpha (HNF4A) is upregulated in PD, but its specific… read more here.
Keywords: mpp induced; parkinson disease; linc00667 regulates; parkinson ... See more keywords
A Secretory Vesicle Failure in Parkinson's Disease Occurs in Human Platelets
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DOI: 10.1002/ana.26335
Abstract: The presence of elevated dopamine (DA) and its major metabolites in the cytosol of neurons has been associated with their vulnerability in Parkinson's disease (PD). Over 99% of the cell's amines are confined to secretory… read more here.
Keywords: parkinson disease; secretory vesicle; failure parkinson; vesicle failure ... See more keywords
Neuroimmunomodulatory properties of DPSCs in an in vitro model of Parkinson's disease
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DOI: 10.1002/iub.1655
Abstract: In neurodegenerative diseases, such as Alzheimer's and Parkinson's, microglial cell activation is thought to contribute to their degeneration by producing neurotoxic compounds. While dental pulp stem cells (DPSCs) have been regarded as the next possible… read more here.
Keywords: properties dpscs; vitro model; parkinson; neuroimmunomodulatory properties ... See more keywords
Comment on: Management of Parkinson's Disease During Pregnancy
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DOI: 10.1002/mdc3.13048
Abstract: I read with interest the detailed literature review on the management of Parkinson’s disease during pregnancy by Young and colleagues. As the authors pointed out, there is a paucity of robust evidence to guide medication… read more here.
Keywords: parkinson; management parkinson; disease pregnancy; parkinson disease ... See more keywords
The Profound Impact of Gastrointestinal Stasis on Levodopa Response in Parkinson's Disease
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DOI: 10.1002/mdc3.13425
Abstract: Gastrointestinal involvement in Parkinson ’ s disease (PD) can impact quality of life through disabling symptoms including nausea, early satiety, anorexia, and constipation and via disruption of oral levodopa absorption and motor and nonmotor fl… read more here.
Keywords: profound impact; parkinson disease; gastrointestinal stasis; impact gastrointestinal ... See more keywords
Rating Scales for Medication Adherence in Parkinson's Disease: A Systematic Review for Critique and Recommendations
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DOI: 10.1002/mdc3.13586
Abstract: Behaviors interfering with medication adherence (MA) are common and often complex in Parkinson's disease (PD), negatively affecting quality of life and undermining the value of clinical trials. The Clinical Outcome Assessments (COA) Scientific Evaluation Committee… read more here.
Keywords: parkinson; parkinson disease; medication adherence; rating scales ... See more keywords
Parkinson's Disease‐Cognitive Rating Scale (PD‐CRS): Normative Data and Mild Cognitive Impairment Assessment in Brazil
Sign Up to like & getrecommendations! Published in 2023 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13657
Abstract: The Parkinson's Disease‐Cognitive Rating Scale (PD‐CRS) assesses posterior‐cortical and frontal‐subcortical cognitive functioning and distinguishes mild cognitive impairment in Parkinson's disease (PD‐MCI); however, it was not evaluated in Brazil. read more here.
Keywords: disease cognitive; parkinson disease; cognitive rating; rating scale ... See more keywords
An update on adaptive deep brain stimulation in Parkinson's disease
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DOI: 10.1002/mds.115
Abstract: Advancing conventional open‐loop DBS as a therapy for PD is crucial for overcoming important issues such as the delicate balance between beneficial and adverse effects and limited battery longevity that are currently associated with treatment.… read more here.
Keywords: stimulation; parkinson; input signals; dbs ... See more keywords
Biomarker‐driven phenotyping in Parkinson's disease: A translational missing link in disease‐modifying clinical trials
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DOI: 10.1002/mds.26913
Abstract: Past clinical trials of putative neuroprotective therapies have targeted PD as a single pathogenic disease entity. From an Oslerian clinicopathological perspective, the wide complexity of PD converges into Lewy bodies and justifies a reductionist approach… read more here.
Keywords: medicine; parkinson; disease modifying; disease ... See more keywords
Vitamin D in the Parkinson Associated Risk Syndrome (PARS) study
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DOI: 10.1002/mds.27127
Abstract: Lower vitamin D levels have been associated with manifest Parkinson's disease, prompting the hypothesis that vitamin D insufficiency or deficiency may increase risk for PD. read more here.
Keywords: associated risk; risk; vitamin parkinson; parkinson ... See more keywords
Interaction between caffeine and polymorphisms ofGRIN2A and CYP1A2 on Parkinson’sdisease risk
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DOI: 10.1002/mds.27279
Abstract: Background Caffeine intake has been inversely associated with Parkinson’s disease (PD) risk. This relationship may be modified by polymorphisms of GRIN2A and CYP1A2 but the results of previous studies have been inconsistent. read more here.
Keywords: polymorphisms ofgrin2a; risk; ofgrin2a cyp1a2; parkinson ... See more keywords