Shared perturbations in the metallome and metabolome of Alzheimer’s, Parkinson’s, Huntington’s, and dementia with Lewy bodies: A systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2020.101152
Abstract: Despite differences in presentation, age-related dementing diseases such as Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HD), and dementia with Lewy bodies (DLB) may share pathogenic processes. This review aims to systematically assemble and compare… read more here.
Keywords: lewy bodies; dementia lewy; alzheimer parkinson; shared perturbations ... See more keywords
On the Right Track to Treat Movement Disorders: Promising Therapeutic Approaches for Parkinson’s and Huntington’s Disease
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2020.571185
Abstract: Movement disorders are neurological conditions in which patients manifest a diverse range of movement impairments. Distinct structures within the basal ganglia of the brain, an area involved in movement regulation, are differentially affected for every… read more here.
Keywords: movement; huntington disease; therapeutic approaches; disease ... See more keywords
Small molecules to perform big roles: The search for Parkinson's and Huntington's disease therapeutics
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.1084493
Abstract: Neurological motor disorders (NMDs) such as Parkinson's disease and Huntington's disease are characterized by the accumulation and aggregation of misfolded proteins that trigger cell death of specific neuronal populations in the central nervous system. Differential… read more here.
Keywords: huntington disease; disease; treatment; small molecules ... See more keywords