Association Between Poor Cognitive Functioning and Risk of Incident Parkinsonism: The Rotterdam Study
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.2248
Abstract: Importance Cognitive dysfunction is a common feature among patients with parkinsonism, including Parkinson disease (PD). However, there is a scarcity of data on cognitive functioning before parkinsonism diagnosis, a stage at which patients may still… read more here.
Keywords: diagnosis; poor cognitive; incident parkinsonism; parkinsonism ... See more keywords
Substantia Nigra Pathology, Contact Sports Play, and Parkinsonism in Chronic Traumatic Encephalopathy.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2024.2166
Abstract: Importance Parkinsonism is associated with traumatic brain injury and chronic traumatic encephalopathy (CTE), a neurodegenerative disease associated with repetitive head impact (RHI) exposure, but the neuropathologic substrates that underlie parkinsonism in individuals with CTE are… read more here.
Keywords: neuronal loss; pathology; contact sports; traumatic encephalopathy ... See more keywords
PLA2G6-associated late-onset parkinsonism in a Sudanese family.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.51781
Abstract: INTRODUCTION The phospholipase A2 group VI gene (PLA2G6) encodes an enzyme that catalyzes the hydrolytic release of fatty acids from phospholipids. Four neurological disorders with infantile, juvenile, or early adult-onset are associated with PLA2G6 genetic… read more here.
Keywords: onset parkinsonism; onset; parkinsonism; late onset ... See more keywords
Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.70121
Abstract: Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and… read more here.
Keywords: characteristics parkinsonism; associated myelopathy; clinical characteristics; htlv associated ... See more keywords
Occupational exposures and parkinsonism among Shanghai women textile workers
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Industrial Medicine"
DOI: 10.1002/ajim.22906
Abstract: BACKGROUND Endotoxin, a contaminant of cotton dust, is an experimental model for parkinsonism (PS). METHODS We investigated associations between exposures to endotoxin, solvents, magnetic fields, and night shift work, and neurologist-determined PS among Shanghai women… read more here.
Keywords: women textile; among shanghai; textile workers; parkinsonism ... See more keywords
Basal Ganglia Atrophy as a Marker for Prodromal X‐Linked Dystonia‐Parkinsonism
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26606
Abstract: In neurodegenerative diseases, the characterization of the prodromal phase is essential for the future application of disease‐modifying therapies. X‐linked dystonia‐parkinsonism is a hereditary neurodegenerative movement disorder characterized by severe adult‐onset dystonia accompanied by parkinsonism. Distinct… read more here.
Keywords: dystonia parkinsonism; non manifesting; linked dystonia; parkinsonism ... See more keywords
Elevated parkinsonism symptoms in autism during middle and older adulthood are linked with psychosocial, physical health, and mental health outcomes
Sign Up to like & getrecommendations! Published in 2024 at "Autism Research"
DOI: 10.1002/aur.3274
Abstract: Evidence is growing for a link between parkinsonism, or the motor symptoms associated with Parkinson's Disease and autism. However, research to date has yet to examine whether the presence of these motoric symptoms impacts critical… read more here.
Keywords: quality; middle older; older adulthood; health ... See more keywords
Higher prevalence of idiopathic normal pressure hydrocephalus‐like MRI features in progressive supranuclear palsy: An imaging reminder of atypical parkinsonism
Sign Up to like & getrecommendations! Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2884
Abstract: The classic triad of idiopathic normal pressure hydrocephalus (NPH) encompass gait disturbance, cognitive impairment, and urinary incontinence. These symptoms overlap with parkinsonism but with distinct treatment. Lacking applicable differentiation also hampers the prediction to therapeutic… read more here.
Keywords: normal pressure; hydrocephalus; parkinsonism; pressure hydrocephalus ... See more keywords
Microstructural white matter alterations in patients with drug induced parkinsonism
Sign Up to like & getrecommendations! Published in 2017 at "Human Brain Mapping"
DOI: 10.1002/hbm.23809
Abstract: Drug‐induced parkinsonism (DIP) is the second most common etiology of parkinsonism. And yet, there is little information on structural imaging in DIP to elucidate the accurate underlying pathomechanisms. To investigate microstructural white matter (WM) in… read more here.
Keywords: drug induced; dip; parkinsonism; microstructural white ... See more keywords
Unsupervised clustering of dopamine transporter PET imaging discovers heterogeneity of parkinsonism
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25155
Abstract: Parkinsonism has heterogeneous nature, showing distinctive patterns of disease progression and prognosis. We aimed to find clusters of parkinsonism based on 18F‐fluoropropyl‐carbomethoxyiodophenylnortropane (FP‐CIT) PET as a data‐driven approach to evaluate heterogenous dopaminergic neurodegeneration patterns. Two… read more here.
Keywords: pet; heterogeneity; pet data; different clinical ... See more keywords
Concurrent AFG3L2 and SPG7 mutations associated with syndromic parkinsonism and optic atrophy with aberrant OPA1 processing and mitochondrial network fragmentation
Sign Up to like & getrecommendations! Published in 2018 at "Human Mutation"
DOI: 10.1002/humu.23658
Abstract: Mitochondrial dynamics and quality control are crucial for neuronal survival and their perturbation is a major cause of neurodegeneration. m‐AAA complex is an ATP‐dependent metalloprotease located in the inner mitochondrial membrane and involved in protein… read more here.
Keywords: opa1 processing; mitochondrial network; optic atrophy; parkinsonism ... See more keywords