Precision dosing‐based optimisation of paroxetine during pregnancy for poor and ultrarapid CYP2D6 metabolisers: a virtual clinical trial pharmacokinetics study
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DOI: 10.1111/jphp.13281
Abstract: Paroxetine has been demonstrated to undergo gestation‐related reductions in plasma concentrations, to an extent which is dictated by the polymorphic state of CYP 2D6. However, knowledge of appropriate dose titrations is lacking. read more here.
Keywords: paroxetine pregnancy; dosing based; optimisation paroxetine; precision dosing ... See more keywords