Employing a Highly Potent Fluorescence Probe to Discover a PARP-1/2 Binder and the Complex Structures Analysis.
Sign Up to like & getrecommendations! Published in 2025 at "ChemMedChem"
DOI: 10.1002/cmdc.202500168
Abstract: Poly (ADP‐ribose) polymerases‐1/2 (PARP‐1/2) has been identified as important antitumor drug targets and the development of PARP‐1/2 inhibitors featuring novel structures is still a promising strategy for cancer treatments. In this work, a highly potent… read more here.
Keywords: parp binder; parp; complex structures; highly potent ... See more keywords