Bridging of DNA breaks activates PARP2–HPF1 to modify chromatin
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DOI: 10.1038/s41586-020-2725-7
Abstract: Breaks in DNA strands recruit the protein PARP1 and its paralogue PARP2 to modify histones and other substrates through the addition of mono- and poly(ADP-ribose) (PAR) 1 – 5 . In the DNA damage responses,… read more here.
Keywords: parp2 hpf1; dna breaks; chromatin; dna ... See more keywords