Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors.
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DOI: 10.1021/acs.jmedchem.2c01452
Abstract: PARP7, a polyadenosine diphosphate-ribose polymerase, has been identified as a negative regulator in type I interferon (IFN) signaling. An overexpression of PARP7 is typically found in a wide range of cancers and can lead to… read more here.
Keywords: parp7; discovery potent; parp7 inhibitor; inhibitor ... See more keywords