Robust immunoglobulin class switch recombination and end joining in Parp9‐deficient mice
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DOI: 10.1002/eji.201646757
Abstract: To mount highly specific and adapted immune responses, B lymphocytes assemble and diversify their antibody repertoire through mechanisms involving the formation of programmed DNA damage. Immunoglobulin class switch recombination (CSR) is triggered by DNA lesions… read more here.
Keywords: class switch; immunoglobulin class; mice; switch recombination ... See more keywords