Inhibition of the substantia nigra pars reticulata produces divergent effects on sensorimotor gating in rats and monkeys
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DOI: 10.1038/s41598-018-27577-w
Abstract: The basal ganglia are an evolutionarily old group of structures, with gross organization conserved across species. Despite this conservation, there is evidence suggesting that anatomical organization of a key output nucleus of the basal ganglia,… read more here.
Keywords: snpr; ppi; across species; nigra pars ... See more keywords
6‐Hydroxydopamine lesion and levodopa treatment modify the effect of buspirone in the substantia nigra pars reticulata
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DOI: 10.1111/bph.15145
Abstract: l‐DOPA‐induced dyskinesia (LID) is considered a major complication in the treatment of Parkinson's disease (PD). Buspirone (5‐HT1A partial agonist) have shown promising results in the treatment of PD and LID, however no 5‐HT‐based treatment has… read more here.
Keywords: nigra pars; pars reticulata; treatment; substantia nigra ... See more keywords
Intraoperative Microelectrode Recordings in Substantia Nigra Pars Reticulata in Anesthetized Rats
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DOI: 10.3389/fnins.2020.00367
Abstract: The Substantia Nigra pars reticulata (SNr) is a promising target for deep brain stimulation (DBS) to treat the gait and postural disturbances in Parkinson’s disease (PD). Positioning the DBS electrode within the SNr is critical… read more here.
Keywords: nigra pars; intraoperative microelectrode; pars reticulata; microelectrode recordings ... See more keywords